• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Stavudine

Stavudine

Product ID S7603
Cas No. 3056-17-5
Purity ≥99%
Product Unit SizeCostQuantityStock
100 mg $52.50 In stock
250 mg $105.00 In stock
1 g $273.00 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Stavudine is a nucleoside analog of thymidine that exhibits antiviral activity. Stavudine is an inhibitor of reverse transcriptase that intercalates with DNA to inhibit viral replication and growth. Administration of stavudine may increase levels of ROS and mitochondrial dysfunction in adipocytes, leading to apoptosis and decreases in proliferation. Stavudine induces autophagy in adipocytes as well, resulting in lipid accumulation and hepatic dysfunction.

Product Info

Cas No.

3056-17-5

Purity

≥99%

Formula

C10H12N2O4

Formula Wt.

224.21

Chemical Name

1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4-dione

IUPAC Name

1-[(2R,5S)-5-(hydroxymethyl)-2, 5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4-dione

Synonym

d4T

Melting Point

159-160°C

Solubility

Water

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

S7603 MSDS PDF

Info Sheet

S7603 Info Sheet PDF

Brochures

Antivirals Booklet

References

Sandhya B, Seetharamappa J. Probing the site-selective binding of an antiretroviral drug, Stavudine to calf thymus DNA. Nucleosides Nucleotides Nucleic Acids. 2013;32(12):660-9. PMID: 24328563.

Stankov MV, Panayotova-Dimitrova D, Leverkus M, et al. Thymidine analogues suppress autophagy and adipogenesis in cultured adipocytes. Antimicrob Agents Chemother. 2013 Jan;57(1):543-51. PMID: 23147731.

Stankov MV, Panayotova-Dimitrova D, Leverkus M, et al. Autophagy inhibition due to thymidine analogues as novel mechanism leading to hepatocyte dysfunction and lipid accumulation. AIDS. 2012 Oct 23;26(16):1995-2006. PMID: 22914580.

Naeger LK, Margot NA, Miller MD. ATP-dependent removal of nucleoside reverse transcriptase inhibitors by human immunodeficiency virus type 1 reverse transcriptase. Antimicrob Agents Chemother. 2002 Jul;46(7):2179-84. PMID: 12069972.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • M1685

    Mevastatin

    Statin; HMG-CoA reductase inhibitor.

    ≥98%
  • G4596

    Glycidamide

    Epoxide metabolite of acrylamide, induces DNA a...

    ≥98%
  • T6903

    Tranylcypromine Hydrochloride

    MAO and histone demethylase LSD1 inhibitor.

    ≥98%
  • N0205

    Nabumetone

    1-Naphthalenacetic acid derivative, NSAID; COX-...

    ≥98%
  • N4524

    NLG919

    Indoleamine-2,3-dioxygenase inhibitor.

    ≥98%
  • G124088

    GDC-1971

    SHP2 inhibitor

    ≥99%
  • M2076

    Metformin Hydrochloride

    AMPK activator.

    ≥98%
  • T5610

    γ-Tocotrienol

    Antioxidant, vitamin E derivative found in vege...

    ≥98%
  • A6971

    ARRY-162

    MEK1/2 and ERK inhibitor.

    ≥99%
  • T3324

    Tigecycline

    Glycylcycline; protein synthesis inhibitor.

    ≥98%
  • G3457

    Ginsenoside Re

    Triterpene saponin found in species of Panax; P...

    ≥98%
  • D5610

    Docosahexaenoic Acid (all cis-4,7,10,13,16,19)

    Essential fatty acid found in fish oil, involve...

    ≥98%
  • S8244

    Sulbactam

    β-lactamase inhibitor.

    ≥98%
  • C6132

    CPI-203

    Triazolothienodiazepine, JQ-1 derivative; BRD i...

    ≥98%
  • P7056

    Procaterol Hydrochloride

    β2-adrenergic agonist.

    ≥98%
  • P577520

    Ponatinib

    pan-Bcr-Abl tyrosine kinase inhibitor.

    ≥99%
  • C5970

    Corydaline

    Alkaloid compound found in Corydalis.

    ≥94%
  • M0248

    Manidipine Dihydrochloride

    Dihydropyridine; L-type and T-type Ca2+ channel...

    ≥99%
  • A5228

    Angiogenin

    Small protein, cleaves RNA.

    ≥98%
  • S7769

    Streptomycin Sulfate

    Aminoglycoside; protein translation inhibitor, ...

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only