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Nabumetone

Product ID N0205
Cas No. 42924-53-8
Purity ≥98%
Product Unit SizeCostQuantityStock
5 g $117.70 In stock
25 g $384.70 In stock
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  • Product Info
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  • Description
  • Product Info
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  • Downloads
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Description

Nabumetone is a 1-naphthalenacetic acid derivative non-steroidal anti-inflammatory drug (NSAID) that inhibits COX-2. Nabumetone exhibits anti-inflammatory, analgesic, anticancer, and chemopreventive activities. In vivo, nabumetone inhibits intestinal carcinogenesis. In vitro, this compound induces apoptosis in colon cancer cells.

Product Info

Cas No.

42924-53-8

Purity

≥98%

Formula

C15H16O2

Formula Wt.

228.29

Chemical Name

4-(6-Methoxy-2-naphthalenyl)-2-butanone

IUPAC Name

4-(6-methoxynaphthalen-2-yl)butan-2-one

Synonym

Arthaxan, Balmox, Consolan, Nabuser, Relafen, Relifen

Melting Point

80°C

Solubility

Soluble in DMSO. Insoluble in water.

Appearance

White or almost white crystalline powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

N0205 MSDS PDF

Info Sheet

N0205 Info Sheet PDF

References

Paul S, Das N, Ghosh S. The effects of aceclofenac and nabumetone in osteoarthritis. JNMA J Nepal Med Assoc. 2009 Apr-Jun;48(174):121-5. PMID: 20387351.

Roy HK, Karoski WJ, Ratashak A, et al. Chemoprevention of intestinal tumorigenesis by nabumetone: induction of apoptosis and Bcl-2 downregulation. Br J Cancer. 2001 May 18;84(10):1412-6. PMID: 11355956.

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