Description
N-Des-2-methylpropan-2-ol Docetaxel is an impurity in the production of paclitaxel.
N-Des-2-methylpropan-2-ol Docetaxel
Product ID T1030
Cas No.
Purity ≥90%
| Product Unit Size | Cost | Quantity | Stock |
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Product Info
| Purity | ≥90% |
|---|---|
| Formula | C39H45NO13 |
| Formula Wt. | 735.78 |
| Chemical Name | N-Des-2-methylpropan-2-ol Docetaxel |
| Synonym | Docetaxel impurity; N-Formyl Docetaxel; (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-Acetoxy-9-(((2R,3S)-3-formamido-2-hydroxy-3-phenylpropanoyl)oxy)-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl Benzoate |
Shipping and Storage
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
Downloads
| MSDS | |
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| Info Sheet |
References
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Nicolaou K, Valiulin R. Synthesis and biological evaluation of new paclitaxel analogs and discovery of potent antitumor agents. Org Biomol Chem. 2013 Jul 7;11(25):4154-4163. PMID: 23685867.
Sanchez-Munoz R, Perez-Mata E, Almagro L, et al. A novel hydroxylation step in the taxane biosynthetic pathway: a new approach to paclitaxel production by synthetic biology. Front Bioeng Biotechnol. 2020 May 13;8::410. PMID: 32528936.
Guo B, Kai G, Jin H, et al. Taxol synthesis. African J Biotechnol. 2006 Jan 2;5(1):15-20.
Wang T, Chen Y, Zhuang W, et al. Transcriptome sequencing reveals regulatory mechanisms of taxol synthesis in Taxus wallichiana var. Mairei. Int J Genomics. 2019 May 2;2019:1596895. PMID: 31192250.