Name: BI-2536
SKU: B3200
Availability: InStock

Description

BI-2536 is a polo-like kinase 1 (PLK1) inhibitor that disrupts mitosis and cell division. BI-2536 exhibits anticancer activity and may induce apoptosis in cancer cells.

Product Info

Cas No.	755038-02-9
Purity	≥98%
Formula	C₂₈H₃₉N₇O₃
Formula Wt.	521.65
Synonym	BI2536
Solubility	Ethanol 100 mg/mL (191.69 mM) DMSO 21 mg/mL (40.25 mM) Water Insoluble
Appearance	Pale yellow to off-white powder

Shipping and Storage

Store Temp	-20°C
Ship Temp	Ambient

Downloads

MSDS	B3200 MSDS PDF
Info Sheet	B3200 Info Sheet PDF

References

Colnaghi R, Wheatley SP. Liaisons between survivin and Plk1 during cell division and cell death. J Biol Chem. 2010 Jul 16;285(29):22592-604. PMID: 20427271.

Zhang J, Yang PL, Gray NS. Targeting cancer with small molecule kinase inhibitors. Nature Reviews Cancer. 2009 Jan;9:28-39.

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BI-2536

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