Description
BI-2536 is a polo-like kinase 1 (PLK1) inhibitor that disrupts mitosis and cell division. BI-2536 exhibits anticancer activity and may induce apoptosis in cancer cells.
Product Unit Size | Cost | Quantity | Stock |
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BI-2536 is a polo-like kinase 1 (PLK1) inhibitor that disrupts mitosis and cell division. BI-2536 exhibits anticancer activity and may induce apoptosis in cancer cells.
Cas No. | 755038-02-9 |
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Purity | ≥98% |
Formula | C28H39N7O3 |
Formula Wt. | 521.65 |
Synonym | BI2536 |
Solubility | Ethanol 100 mg/mL (191.69 mM) DMSO 21 mg/mL (40.25 mM) Water Insoluble |
Appearance | Pale yellow to off-white powder |
Store Temp | -20°C |
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Ship Temp | Ambient |
MSDS | |
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Info Sheet |
Colnaghi R, Wheatley SP. Liaisons between survivin and Plk1 during cell division and cell death. J Biol Chem. 2010 Jul 16;285(29):22592-604. PMID: 20427271.
Zhang J, Yang PL, Gray NS. Targeting cancer with small molecule kinase inhibitors. Nature Reviews Cancer. 2009 Jan;9:28-39.