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Timolol Maleate

Product ID T3350
Cas No. 26921-17-5
Purity ≥98%
Product Unit SizeCostQuantityStock
100 mg $94.40 In stock
250 mg $199.30 In stock
1 g $566.60 In stock
Bulk Quote

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  • Product Info
  • Shipping and Storage
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  • References
  • Description
  • Product Info
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  • Downloads
  • References
  • Custom Order

Description

Timolol is a non-selective β-adrenergic receptor antagonist that exhibits antihypertensive activity. Timolol is clinically used to induce vascular relaxation in the ciliary artery. Timolol decreases intraocular pressure in the treatment of glaucoma.

Product Info

Cas No.

26921-17-5

Purity

≥98%

Formula

C13H24N4O3S • C4H4O4

Formula Wt.

432.50

Chemical Name

(2S)-1-[(1,1-Dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-2-propanol maleate

IUPAC Name

(Z)-but-2-enedioic acid;(2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2, 5-thiadiazol-3-yl)oxy]propan-2-ol

Synonym

Betime, Blocadren, Istalol, Timacar, Timoptol: Proflax

Melting Point

202-203°C

Solubility

Soluble in water, methanol, and ethanol.

Appearance

White powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

T3350 MSDS PDF

Info Sheet

T3350 Info Sheet PDF

References

Johnson TV, Fan S, Zhan G, et al. Efficacy and mechanisms of intraocular pressure reduction with latanoprost and timolol in participants with ocular hypertension: a comparison of 1 and 6 weeks of treatment. J Glaucoma. 2010 Aug;19(6):356-64. PMID: 20179619.

Dong Y, Ishikawa H, Wu Y, et al. Effect and mechanism of betaxolol and timolol on vascular relaxation in isolated rabbit ciliary artery. Jpn J Ophthalmol. 2006 Nov-Dec;50(6):504-8. PMID: 17180523.

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