• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
15,16-Dehydrocafestol

15,16-Dehydrocafestol

Product ID D1731
Cas No.
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $337.10 In stock
10 mg $510.50 In stock
25 mg $1,021.00 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

15,16-Dehydrocafestol is a diterpene found in roasted coffee. This compound is a dehydration product of cafestol, which inhibits increases in pro-fibrotic cytokine TGF-β in models of liver damage and induces apoptosis through regulation of Sp1 signaling. 15,16-Dehydrocafestol exhibits anti-fibrotic, hepatoprotective, and anticancer activities. It may also induce apoptosis in malignant pleural mesothelioma cells.

Product Info

Purity

≥98%

Formula

C20H26O2

Formula Wt.

298.42

Synonym

Dehydrocafestol

Melting Point

110-112°C

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

D1731 MSDS PDF

Info Sheet

D1731 Info Sheet PDF

References

Arauz J, Moreno MG, Cortés-Reynosa P, et al. Coffee attenuates fibrosis by decreasing the expression of TGF-β and CTGF in a murine model of liver damage. J Appl Toxicol. 2013 Sep;33(9):970-9. PMID: 22899499.

Lee KA, Chae JI, Shim JH. Natural diterpenes from coffee, cafestol and kahweol induce apoptosis through regulation of specificity protein 1 expression in human malignant pleural mesothelioma. J Biomed Sci. 2012 Jun 26;19:60. PMID: 22734486.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • T0109

    13-Acetyl-9-dihydrobaccatin-III

    Found in Taxus, starting material for synthesis...

    ≥98%
  • C5864

    Coptisine Chloride, synthetic

    Isoquinoline alkaloid found in a variety of pla...

    ≥98%
  • A7577

    Astilbin

    Flavonoid found in various plant sources.

    ≥99%
  • T8006

    Tubastatin A Hydrochloride

    HDAC6/10 inhibitor.

    ≥98%
  • C1621

    CEF4

    Peptide, vSrc-induced cytokine.

    ≥95%
  • E0403

    Ebastine

    Histamine H1 antagonist.

    ≥98%
  • W5727

    Wogonoside

    Flavonoid glycoside found in Scutellaria.

    ≥98%
  • A1318

    Adenine

    Endogenous purine nucleotide base, required for...

    ≥98%
  • L3551

    Limonin Glucoside

    Furanolactone found in Citrus.

    ≥95%
  • O1179

    n-Octyl-4-methylcaffeate

    Derivative of methyl caffeate, hydroxycinnamic ...

    ≥98%
  • C577524

    Concanamycin A

    Macrolide lactone antibiotic.

    ≥98%
  • C2942

    Mechlorethamine Hydrochloride

    Nitrogen mustard, DNA alkylator.

    ≥98%
  • A5272

    Angiotensin, dog/rat

    Peptide, derivative of AT I, cleavage product o...

    ≥95%
  • C0260

    Capsanthin

    Carotenoid originally found in Capsicum. Color ...

    Color value:100
  • M1613

    Medroxyprogesterone 17-Acetate

    Synthetic steroid used in HRT; PR, AR, glucocor...

    ≥99%
  • T8145

    Tulobuterol Hydrochloride

    β2-adrenergic agonist.

    ≥98%
  • C458567

    Clofazimine

    Antibacterial (Antimyobacterial) agent.

    ≥99%
  • C1176

    CCT-128930

    Pyrrolopyrimidine; Akt inhibitor.

    ≥98%
  • M1626

    Megestrol Acetate

    Synthetic progestogen, orexigenic.

    ≥98%
  • C5773

    Cortistatin-14

    Endogenous neuropeptide, somatostatin analog; s...

    ≥95%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only