Description
Altiratinib is an inhibitor of c-MET, Tie-2, and VEGFR that exhibits anticancer chemotherapeutic activity. In ovarian cancer models, this compound inhibits cell growth and migration and decreases tumor burden.
Product Unit Size | Cost | Quantity | Stock |
---|
Altiratinib is an inhibitor of c-MET, Tie-2, and VEGFR that exhibits anticancer chemotherapeutic activity. In ovarian cancer models, this compound inhibits cell growth and migration and decreases tumor burden.
Cas No. | 1345847-93-9 |
---|---|
Purity | ≥98% |
Formula | C26H21F3N4O4 |
Formula Wt. | 510.46 |
Chemical Name | 1-N'-[4-[2-(cyclopropanecarbonylamino)pyridin-4-yl]oxy-2,5-difluorophenyl]-1-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide |
IUPAC Name | N-[4-({2-[(Cyclopropylcarbonyl)amino]-4-pyridinyl}oxy)-2,5-difluorophenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide |
Synonym | DCC-2701, DP-5164 |
Solubility | DMSO: 33mg/mL |
Store Temp | Ambient |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Kwon Y, Smith BD, Zhou Y, et al. Effective inhibition of c-MET-mediated signaling, growth and migration of ovarian cancer cells is influenced by the ovarian tissue microenvironment. Oncogene. 2015 Jan 8;34(2):144-53. PMID: 24362531.
PI3K inhibitor, microtubule polymerization inhi...
PPARγ coactivator-1α expression stimulator.
Imidzoline derivative; MDM2 inhibitor.
Vitamin D analog.
Indoloquinazoline alkaloid found in Evodia; COX...
Aminoquinoline, binds heme, causes cell lysis.<...
Benzophenanthridine alkaloid found in various p...
BTK and IL-2-inducible kinase inhibitor.
Aldosterone antagonist.
Loop diuretic; NKCC symporter inhibitor, CFTR C...
Polyphenolic compound present in black tea.
Tankyrase inhibitor.
Tricyclic antidepressant; potential D1/2 antago...
Folate source co-administered with methotrexate...
Synthetic taxol synthesis intermediate; microtu...
Pheniramine derivative; histamine H1 and mAChR ...
Docetaxel impurity
Carotene pigment found in red and green fruits ...
Loop diuretic; NKCC symporter and KCC2 co-trans...
Carotenoid found in shrimp, salmon, and algae.<...