• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Colchicine

Colchicine

Product ID C5645
Cas No. 64-86-8
Purity ≥97%
Product Unit SizeCostQuantityStock
500 mg $92.00 In stock
1 g $142.90 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Colchicine is an anti-inflammatory anti-mitotic compound originally found in Colchicum; it is clinically used to treat gout. Colchicine binds tubulin and inhibits microtubule polymerization, inhibiting inflammasome activation, cytokine generation, and chemotaxis. Colchicine inhibits neutrophil motility. The anticancer potential of colchicine is limited by its high toxicity.

Product Info

Cas No.

64-86-8

Purity

≥97%

Formula

C22H25NO6

Formula Wt.

399.44

Chemical Name

N-[(7S)-5,6,7,9-Tetrahydro-1,10,3,10-tetramethoxy-9- oxobenzo[a]heptalen-7-yl]acetamide

IUPAC Name

N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6, 7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide

Melting Point

142-150°C

Solubility

Soluble in water (40 mg/mL), ethanol (7 mg/ml), DMSO (14 mg/ml), or chloroform. Insoluble in petr. ether.

Appearance

Faintly yellow crystal powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

C5645 MSDS PDF

Info Sheet

C5645 Info Sheet PDF

References

Dalbeth N, Lauterio TJ, Wolfe HR. Mechanism of Action of Colchicine in the Treatment of Gout. Clin Ther. 2014 Aug 21. [Epub ahead of print]. PMID: 25151572.

Ching JK, Ju JS, Pittman SK, et al. Increased autophagy accelerates colchicine-induced muscle toxicity. Autophagy. 2013 Dec;9(12):2115-25. PMID: 24184927.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • M0803

    MC1568

    HDAC inhibitor. May reduce blood pressure in hy...

    ≥98%
  • T6933

    Trichostatin A

    HDAC inhibitor, mammalian RNA splicing modulato...

    ≥98%
  • Z0252

    Zanamivir

    Neuraminidase inhibitor.

    ≥98%
  • S0048

    Salicin

    Alcoholic β-glucoside found in willow bark, sa...

    ≥98%
  • A5061

    Ampalex

    Benzylpiperidine; AMPA potentiator.

    ≥98%
  • P2512

    S-(N-Phenethylthiocarbamoyl)-L-cysteine

    Cysteine-ITC conjugate, antioxidant.

    ≥98%
  • M1774

    2-Mercaptoethanesulfonate Sodium

    Organosulfur, antioxidant.

    ≥98%
  • G0175

    Gastric Inhibitory Peptide, human

    Endogenous peptide hormone, somatostatin analog...

    ≥95%
  • C0365

    Carvedilol

    FIASMA; α1- and β1/2-adrenergic antagonist.

    ≥98%
  • I0516

    I-BET151

    BRD2/3/4 inhibitor.

    ≥98%
  • T1968

    Terpinen-4-ol

    Monoterpene found in various plant sources.

    ≥98%
  • X4400

    XL-228

    Abl (T315I) inhibitor.

    ≥98%
  • A0918

    N-Acetyl-L-Cysteine

    Cysteine derivative, antioxidant, ROS scavenger...

    ≥98%
  • D3215

    Didymin

    Flavonoid glycoside found in citrus fruit.

    ≥98%
  • B1668

    Berteroin

    Thio sulforaphane analog, ITC.

    ≥97%
  • C0246

    Calcimycin

    Polyether pyrrole, divalent cation ionophore.

    ≥98%
  • C1613

    Cediranib

    VEGFR inhibitor.

    ≥98%
  • I7456

    1-Isothiocyanato-7-(methylsulfinyl)-heptane

    ITC, radical scavenger.

    ≥98%
  • V182685

    Verdinexor

    CRM1/XPO1 inhibitor.

    ≥99%
  • V0252

    Vancomycin Hydrochloride

    Glycopeptide, binds D-Ala-D-Ala; cell wall synt...

    ≥1050 IU/mg, bio assay

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only