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Levofloxacin Hemihydrate

Levofloxacin Hemihydrate

Product ID L1785
Cas No. 138199-71-0
Purity ≥98%
Product Unit SizeCostQuantityStock
500 mg $50.90 In stock
1 g $71.50 In stock
5 g $255.30 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Levofloxacin is the S-(−) isomer of ofloxacin. Levofloxacin is a fluoroquinolone antibiotic that inhibits DNA gyrase and topoisomerase IV; it exhibits antibacterial efficacy against gram negative and gram positive bacteria. Levofloxacin also displays anticancer activity, as when complexed with gold(III), it binds DNA and inhibits cellular proliferation in several cancer cell lines.

Product Info

Cas No.

138199-71-0

Purity

≥98%

Formula

(C18H20FN3O4)2 • H2O

Formula Wt.

370.4

IUPAC Name

(2S)-7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid;hydrate

Synonym

S-(−)-Ofloxacin,

Appearance

Slight yellow crystalline powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

L1785 MSDS PDF

Info Sheet

L1785 Info Sheet PDF

References

Fu Y, Zhang W, Wang H, et al. Specific patterns of gyrA mutations determine the resistance difference to ciprofloxacin and levofloxacin in Klebsiella pneumoniae and Escherichia coli. BMC Infect Dis. 2013 Jan 7;13:8. PMID: 23295059.

Gouvea LR, Garcia LS, Lachter DR, et al. Atypical fluoroquinolone gold(III) chelates as potential anticancer agents: relevance of DNA and protein interactions for their mechanism of action. Eur J Med Chem. 2012 Sep;55:67-73. PMID: 22835721.

Drlica K, Zhao X. DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol Mol Biol Rev. 1997 Sep;61(3):377-92. PMID: 9293187.

Custom Order

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