LKT Labs

Biochemicals for Life Science Research

Diallyl Tetrasulfide

Product ID D3203
Cas No. 2444-49-7
Purity ≥90%
Product Unit SizeCostQuantityStock
5 mg $121.10 In stock
25 mg $346.10 In stock
100 mg $741.60 In stock
Bulk Quote

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Description

Diallyl tetrasulfide is an organosulfur that displays anticancer, antioxidative, and antimicrobial properties. In vitro, diallyl tetrasulfide increases reactive oxygen species (ROS) and heme oxygenase-1 levels and inhibits microtubule polymerization, inducing mitotic arrest. Diallyl tetrasulfide exhibits antibacterial and antifungal benefit against many microbes, including including Staphylococcus aureus, methicillin-resistant Staphylococcus aureus (MRSA), and several species of Candida and Aspergillus. Additionally, this compound decreases cadmium-mediated oxidative damage in several animal models, increasing levels of superoxide dismutase, glutathione peroxidase, and other glutathione metabolizing enzymes.

Product Info

Cas No.

2444-49-7
Purity

≥90%
Formula

C6H10S4
Formula Wt.

210.40
Chemical Name

3-(prop-2-enyltetrasulfanyl)prop-1-ene
IUPAC Name

3-(prop-2-enyltetrasulfanyl)prop-1-ene
Synonym

Allyl tetrasulfide
Appearance

Light Yellow Oil

Shipping and Storage

Store Temp

-80°C
Ship Temp

Blue Ice

Downloads

MSDS

D3203 MSDS PDF
Info Sheet

D3203 Info Sheet PDF

References

Saidu NE, Abu Asali I, Czepukojc B, et al. Comparison between the effects of diallyl tetrasulfide on human retina pigment epithelial cells (ARPE-19) and HCT116 cells. Biochim Biophys Acta. 2013 Nov;1830(11):5267-76. PMID: 23948592.

Kelkel M, Cerella C, Mack F, et al. ROS-independent JNK activation and multisite phosphorylation of Bcl-2 link diallyl tetrasulfide-induced mitotic arrest to apoptosis. Carcinogenesis. 2012 Nov;33(11):2162-71. PMID: 22822094.

Ponnusamy M, Pari L. Protective role of diallyl tetrasulfide on cadmium-induced testicular damage in adult rats: a biochemical and histological study. Toxicol Ind Health. 2011 Jun;27(5):407-16. PMID: 21245201.

Tsao SM, Yin MC. In-vitro antimicrobial activity of four diallyl sulphides occurring naturally in garlic and Chinese leek oils. J Med Microbiol. 2001 Jul;50(7):646-9. PMID: 11444776.

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