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7,8-Dihydrokawain is a kavalactone originally found in Piper methysticum (kava plant) that exhibits neuroprotective activity. 7,8-Dihydrokawain activates Nrf2 in neurons and astroglia, protecting against amyloid-β (Aβ)-induced neurotoxicity.
| Cas No. | 587-63-3 |
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| Purity | ≥98% |
| Formula | C14H16O3 |
| Formula Wt. | 232.28 |
| IUPAC Name | 4-methoxy-2-(2-phenylethyl)-2,3-dihydropyran-6-one |
| Synonym | DHK, Dihydrokawain, Marindinin |
| Melting Point | 56-60°C |
| Solubility | Soluble in DMSO and methanol. |
| Appearance | White/Off White Crystalline Powder |
| Store Temp | -20°C |
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| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Xuan TD, Elzaawely AA, Fukuta M, et al. Herbicidal and Fungicidal Activities of Lactones in Kava (Piper methysticum). J Agric Food Chem. 2006 Feb 8;54(3):720-5. PMID: 16448174.