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Brompheniramine Maleate

Brompheniramine Maleate

Product ID B7058
Cas No. 980-71-2
Purity ≥98%
Product Unit SizeCostQuantityStock
10 mg $92.60 In stock
25 mg $165.40 In stock
100 mg $385.90 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Brompheniramine is a halogenated antihistamine derivative of pheniramine that exhibits anticholinergic and neuromodulatory activities. Brompheniramine inhibits the H1 histamine receptor and also displays non-selective inhibition of muscarinic acetylcholine receptors (mAChRs). Brompheniramine inhibits histamine-induced vasodilation and also potentiates the effects of opioid analgesics. Additionally, brompheniramine is the parent compound of zimelidine, a selective serotonin reuptake inhibitor (SSRI) that exhibits antidepressant activity; zimelidine inhibits pre-synaptic 5-HT reuptake and may inhibit the serotonin transporter (SERT) or monoamine oxidase B (MAO-B).

Product Info

Cas No.

980-71-2

Purity

≥98%

Formula

C16H19BrN2 • C4H4O4

Formula Wt.

435.31

Chemical Name

3-(4-bromophenyl)-N,N-dimethyl-3-pyridin-2-ylpropan-1-amine;(Z)-but-2-enedioic acid

IUPAC Name

3-(4-bromophenyl)-N,N-dimethyl-3-pyridin-2-ylpropan-1-amine;(Z)-but-2-enedioic acid

Synonym

brompheniramine hydrogen maleate, parabromdylamine maleate, Veltane

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

B7058 MSDS PDF

Info Sheet

B7058 Info Sheet PDF

References

Egashira T, Takayama F, Yamanaka Y. The inhibition of monoamine oxidase activity by various antidepressants: differences found in various mammalian species. Jpn J Pharmacol. 1999 Sep;81(1):115-21. PMID: 10580379.

Yasuda SU, Yasuda RP. Affinities of brompheniramine, chlorpheniramine, and terfenadine at the five human muscarinic cholinergic receptor subtypes. Pharmacotherapy. 1999 Apr;19(4):447-51. PMID: 10212017.

Tatsumi M, Groshan K, Blakely RD, et al. Pharmacological profile of antidepressants and related compounds at human monoamine transporters. Eur J Pharmacol. 1997 Dec 11;340(2-3):249-58. PMID: 9537821.

Dachman WD, Bedarida G, Blaschke TF, et al. Histamine-induced venodilation in human beings involves both H1 and H2 receptor subtypes. J Allergy Clin Immunol. 1994 Mar;93(3):606-14. PMID: 8151062.

Ogren SO, Ross SB, Hall H, et al. The pharmacology of zimelidine: a 5-HT selective reuptake inhibitor. Acta Psychiatr Scand Suppl. 1981;290:127-51. PMID: 6452789.

Custom Order

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