Description
Acyclovir is a guanosine nucleoside analog that exhibits antiviral activity. Acyclovir is clinically used to treat infections of the herpes simplex virus; it inhibits viral DNA polymerase and D-amino acid oxidase.
Product Unit Size | Cost | Quantity | Stock |
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Acyclovir is a guanosine nucleoside analog that exhibits antiviral activity. Acyclovir is clinically used to treat infections of the herpes simplex virus; it inhibits viral DNA polymerase and D-amino acid oxidase.
Cas No. | 59277-89-3 |
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Purity | ≥98% |
Formula | C8H11N5O3 |
Formula Wt. | 225.20 |
Chemical Name | Acycloguanosine; Vipral; Zovirax |
IUPAC Name | 2-amino-9-(2-hydroxyethoxymethyl)-3H-purin-6-one |
Melting Point | 256.5-257°C |
Solubility | Slightly soluble in water (0.7 mg/mL). Soluble in 1 M HCl (50 mg/mL), DMSO (7 mg/mL). |
Appearance | White Crystalline Powder |
Store Temp | Ambient |
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Ship Temp | Ambient |
MSDS | |
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Info Sheet |
James SH, Prichard MN. Current and future therapies for herpes simplex virus infections: mechanism of action and drug resistance. Curr Opin Virol. 2014 Jul 15;8C:54-61. PMID: 25036916.
Katane M, Matsuda S, Saitoh Y, et al. The antiviral drug acyclovir is a slow-binding inhibitor of (D)-amino acid oxidase. Biochemistry. 2013 Aug 20;52(33):5665-74. PMID: 23859606.
Elion GB. Mechanism of action and selectivity of acyclovir. Am J Med. 1982 Jul 20;73(1A):7-13. PMID: 6285736.
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