Name: C59
SKU: C0800
Availability: InStock

Description

C59 is a PORCN inhibitor that exhibits anticancer chemotherapeutic activity, inhibiting the progression of mammary tumors in vivo by downregulating Wnt signaling.

Product Info

Cas No.	1243243-89-1
Purity	≥98%
Formula	C₂₅H₂₁N₃O
Formula Wt.	379.45
Chemical Name	2-[4-(2-methylpyridin-4-yl)phenyl]-N-(4-pyridin-3-ylphenyl)acetamide
IUPAC Name	2-[4-(2-methylpyridin-4-yl)phenyl]-N-(4-pyridin-3-ylphenyl)acetamide
Synonym	Wnt-C59
Solubility	DMSO 76 mg/mL (200.28 mM) Water Insoluble Ethanol Insoluble
Appearance	White to off white powder

Shipping and Storage

Store Temp	-20°C
Ship Temp	Ambient

Downloads

MSDS	C0800 MSDS PDF
Info Sheet	C0800 Info Sheet PDF

References

Proffitt KD, Madan B, Ke Z, et al. Pharmacological inhibition of the Wnt acyltransferase PORCN prevents growth of WNT-driven mammary cancer. Cancer Res. 2013 Jan 15;73(2):502-7. PMID: 23188502.

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C59

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