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S-Methyl-L-cysteine

Product ID M1564
Cas No. 1187-84-4
Purity ≥99%
Product Unit SizeCostQuantityStock
1 g $44.00 In stock
5 g $97.00 In stock
25 g $387.90 Please Inquire
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Description

S-Methyl-L-cysteine (SMLC) is found in onions, garlic, cabbage, and legumes; it exhibits antioxidative, neuroprotective, and anti-obesity activities. SMLC is a substrate of the catalytic antioxidant system mediated by methionine sulfoxide reductase A. This compound is involved in extracellular D-serine signaling and enzymatic reduction of oxidative stress, holding potential therapeutic benefit for diseases characterized by NMDA-receptor dysfunction, such as Parkinson’s Disease. SMLC also acts as a potential anti-obesity agent, inhibiting oil drop formation in rat white pre-adipose tissue.

Product Info

Cas No.

1187-84-4

Purity

≥99%

Formula

C4H9NO2S

Formula Wt.

135.18

IUPAC Name

(2R)-2-amino-3-methylsulfanylpropanoic acid

Synonym

(R)-2-Amino-3-(methylmercapto)propionic acid, SMLC

Melting Point

219 -221°C

Solubility

Soluble in 0.1 N NaOH (1% w/v) or water (50 mg/mL).

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

M1564 MSDS PDF

Info Sheet

M1564 Info Sheet PDF

Brochures

Natural Products Flyer

References

Ishiwata S, Ogata S, Umino A, et al. Increasing effects of S-methyl-L-cysteine on the extracellular D-serine concentrations in the rat medial frontal cortex. Amino Acids. 2013 May;44(5):1391-5. PMID: 23417484.

Yoshinari O, Shiojima Y, Igarashi K. Anti-obesity effects of onion extract in Zucker diabetic fatty rats. Nutrients. 2012 Oct 22;4(10):1518-26. PMID: 23201769.

Wassef R, Haenold R, Hansel A, et al. Methionine sulfoxide reductase A and a dietary supplement S-methyl-L-cysteine prevent Parkinson's-like symptoms. J Neurosci. 2007 Nov 21;27(47):12808-16. PMID: 18032652.

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