• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Theaflavin-3,3’-digallate

Theaflavin-3,3’-digallate

Product ID T286163
Cas No. 30462-35-2
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $202.90 In stock
5 mg $751.40 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Theaflavin-3,3’-digallate is a polyphenolic compound found in black tea. The theaflavins are formed during the enzymatic oxidation of catechins, which happens during processing of the fresh tea leaves. Theaflavin-3,3’-digallate has also shown inhibitory effects on ovarian cancer cells OVCAR-3 and A2780/CP70 by inducing apoptosis and impairing tumor angiogenesis. In addition, theaflavin-3,3’-digallate was found to produce notably efficient reactive oxygen species scavenging activity by a chemiluminescence assay. Theaflavin-3,3’-digallate was also shown to produce chemopreventive effects through the inhibition of the EGFR signaling pathway as a result of EGFR down-regulation.

Product Info

Cas No.

30462-35-2

Purity

≥98%

Formula

C43H32O20

Formula Wt.

868.71

Chemical Name

[(2R,3R)-2-[1-[(2R,3R)-5,7-Dihydroxy-3-(3,4,5-trihydroxybenzoyl)oxy-3,4-dihydro-2H-chromen-2-yl]-3,4,5-trihydroxy-6-oxobenzo[7]annulen-8-yl]-5,7-dihydroxy-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate

IUPAC Name

(3,4,5-Trihydroxy-6-oxo-6H-benzo[7]annulene-1,8-diyl)bis[(2R,3R)-5,7-dihydroxy-3,4-dihydro-2H-chromene-2,3-diyl] bis(3,4,5-trihydroxybenzoate)

Synonym

Theaflavin digallate

Melting Point

226-230°C dec

Solubility

0.1 mg/mL water.

Appearance

Brick red powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

T286163 MSDS PDF

Info Sheet

T286163 Info Sheet PDF

References

Gao Y, Rankin GO, Tu Y, et al. Inhibitory effects of the four main theaflavin derivatives found in black tea on ovarian cancer cells. Anticancer Res. 2016 Feb;36(2):643-651. PMID: 26851019.

Wu YY, Li W, Xu Y, et al. Evaluation of the antioxidant effects of four main theaflavin derivatives through chemiluminescence adn DNA damage analyses. J Zhejiang Univ Sci B. 2011 Sep;12(9):744-751. PMID: 21887850.

Mizuno H, Cho YY, Zhu F, et al. Theaflavin-3,-3’-digallate induces epidermal growth factor receptor downregulation. Mol Carcinog. 2006 Mar;45(3):204-212. PMID: 16353237.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • G0245

    Gallocatechin Gallate

    Polyphenol found in Camilla sinensis; HIV integ...

    ≥98%
  • I4000

    Ikarugamycin

    Protein translation inhibitor.

    ≥98%
  • D3320

    Difenoconazole

    Triazole; 14-α demethylase inhibitor, potentia...

    ≥98%
  • T3098

    Thymosin β-4 Acetate

    Endogenous peptide; actin polymerization inhibi...

    ≥95%
  • T5604

    Tobramycin, Free Base

    Aminoglycoside; protein translation inhibitor.<...

    ≥98%
  • Z160021

    Zearalanone

    Mycotoxin.

    ≥97%
  • A6982

    Artesunate

    Sesquiterpene lactone derived from Artemesia.

    ≥98%
  • I7557

    1-Isothiocyanato-6-(methylsulfonyl)-hexane

    Synthetic ITC, erysolin analog.

    ≥98%
  • C0243

    Calcitonin Gene Related Peptide (8-37), human

    Calcitonin-family peptide frgament, involved in...

    ≥95%
  • B3472

    4,4′-(1,1′-Biphenyl-4,4′-diyldioxy)dianiline

    Potential VEGFR2, Met, RET, Axl, Ron, PDGFR, FG...

    ≥98%
  • J889280

    JWH 015

    Cannabinoid receptor 2 selective agonist.

    ≥98%
  • I7155

    Isoindigo

    Potential AhR binding agent.

    ≥98%
  • T8153

    Tunicamycin

    Nucleoside antibiotic mixture; GlcNAc phosphotr...

    ≥98%
  • A2077

    Afatinib

    EGFR inhibitor.

    ≥98%
  • T0249

    Tamibarotene

    RARα/β agonist.

    ≥98%
  • S336486

    Simeprevir

    NS3/4A inhibitor

    ≥99%
  • P6959

    Prothionamide

    Nicotinic acid derivative; InhA inhibitor.

    ≥98%
  • T0205

    3”,4”-Dehydropaclitaxel C

    Semi-synthetic taxane.

    ≥95%
  • V0146

    Valsartan

    AT1 inhibitor.

    ≥98%
  • T0097

    10-Deacetyltaxol B

    Diterpene found in Taxus; potential microtubule...

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only