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Isoindigo

Isoindigo

Product ID I7155
Cas No. 476-34-6
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $57.10 In stock
100 mg $75.10 In stock
250 mg $147.20 In stock
1 g $450.80 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Isoindigo inhibits proliferation in various leukemia and cancer cell lines, displaying anticancer activity. Isoindigo and its derivatives may also bind the aryl hydrocarbon receptor (AhR). Additionally, similar compounds show chemotherapeutic benefits in animal models of leukemia.

Product Info

Cas No.

476-34-6

Purity

≥98%

Formula

C16H10N2O2

Formula Wt.

262.27

IUPAC Name

(3E)-3-(2-Oxo-1,2-dihydro-3H-indol-3-ylidene)-1,3-dihydro-2H-indol-2-one

Synonym

Isoindigotin

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

I7155 MSDS PDF

Info Sheet

I7155 Info Sheet PDF

References

Wee XK, Yang T, Go ML. Exploring the anticancer activity of functionalized isoindigos: synthesis, drug-like potential, mode of action and effect on tumor-induced xenografts. ChemMedChem. 2012 May;7(5):777-91. PMID: 22416043.

Bouchikhi F, Anizon F, Moreau P. Synthesis and antiproliferative activities of isoindigo and azaisoindigo derivatives. Eur J Med Chem. 2008 Apr;43(4):755-62. PMID: 17628214.

Nishiumi S, Yamamoto N, Kodoi R, et al. Antagonistic and agonistic effects of indigoids on the transformation of an aryl hydrocarbon receptor. Arch Biochem Biophys. 2008 Feb 15;470(2):187-99. PMID: 18086550.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
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  • This field is for validation purposes and should be left unchanged.

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