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Calcitonin Gene Related Peptide (8-37), human

Calcitonin Gene Related Peptide (8-37), human

Product ID C0243
Cas No. 119911-68-1
Purity ≥95%
Product Unit SizeCostQuantityStock
0.5 mg $310.80 In stock
1 mg $527.40 In stock
2.5 mg $932.30 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Calcitonin gene-related peptide (CGRP) (8-37) inhibits the CGRP receptor and is used in research studies to examine the effects of CGRP. CGRP (8-37) inhibits the effects of ghrelin and induces caspase 3-mediated apoptosis in retinal cells of animal models of coronary artery occlusion. Like CGRP, this fragment likely binds RAMP1 and CGRP receptors.

Product Info

Cas No.

119911-68-1

Purity

≥95%

Formula

C139H230N44O38

Formula Wt.

3125.65

IUPAC Name

L-Valyl-L-threonyl-L-histidyl-L-arginyl-L-leucyl-L-alanylglycyl-L-leucyl-L-leucyl-L-seryl-L-arginyl-L-serylglycylglycyl-L-valyl-L-valyl-L-lysyl-L-asparaginyl-L-asparaginyl-L-phenylalanyl-L-valyl-L-pro lyl-L-threonyl-L-asparaginyl-L-valylglycyl-L-seryl-L-lysyl-L-alanyl-L-phenylalaninamide

Synonym

CGRP (8-37)

Solubility

Soluble in water (0.5 mg/mL).

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

C0243 MSDS PDF

Info Sheet

C0243 Info Sheet PDF

References

Nguyen VT, Wu Y, Guillory AN, et al. Delta-opioid augments cardiac contraction through β-adrenergic and CGRP-receptor co-signaling. Peptides. 2012 Jan;33(1):77-82. PMID: 22108711.

Yang JH, Zhang YQ, Guo Z. Endogenous CGRP protects retinal cells against stress induced apoptosis in rats. Neurosci Lett. 2011 Aug 26;501(2):83-5. PMID: 21763400.

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