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Glucagon (19-29), human

Product ID G4479
Cas No. 64790-15-4
Purity ≥95%
Product Unit SizeCostQuantityStock
1 mg $68.00 Please Inquire
2 mg $115.60 Please Inquire
5 mg $204.10 Please Inquire
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  • Description
  • Product Info
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Description

Glucagon (19-29) is also known as miniglucagon, an endogenous short peptide co-released with glucagon. Miniglucagon inhibits insulin secretion from pancreatic β-cells in a Ca2+-dependent manner.

Product Info

Cas No.

64790-15-4

Purity

≥95%

Formula

C61H89N15O18S

Formula Wt.

1352.54

IUPAC Name

(3S)-4-[[(2S)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[ (2S)-4-amino-1-[[(1S,2S)-1-carboxy-2-hydroxypropyl]amino]-1, 4-dioxobutan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4- methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino] -1, 5-dioxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxo-3- phenylpropan-2-yl]amino]-3-[[(2S)-5-amino-2-[[(2S)-2-aminopropanoyl] amino]-5-oxopentanoyl]amino]-4-oxobutanoic acid

Synonym

Des(1-18) glucagon, Miniglucagon

Solubility

Soluble in water, DMSO.

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

G4479 MSDS PDF

Info Sheet

G4479 Info Sheet PDF

References

Bataille D, Fontés G, Costes S, et al. The glucagon-miniglucagon interplay: a new level in the metabolic regulation. Ann N Y Acad Sci. 2006 Jul;1070:161-6. PMID: 16888159.

Dalle S, Fontés G, Lajoix AD, et al. Miniglucagon (glucagon 19-29): a novel regulator of the pancreatic islet physiology. Diabetes. 2002 Feb;51(2):406-12. PMID: 11812748.

Dalle S, Smith P, Blache P, et al. Miniglucagon (glucagon 19-29), a potent and efficient inhibitor of secretagogue-induced insulin release through a Ca2+ pathway. J Biol Chem. 1999 Apr 16;274(16):10869-76. PMID: 10196164.

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