Description
JAK2 inhibitor V (Z3) is an inhibitor of JAK2 that exhibits anticancer activity. In erythroleukemia cells, this compound induces cell cycle arrest and suppresses cellular proliferation.
JAK2 Inhibitor V
Product ID J0240
Cas No. 195371-52-9
Purity ≥98%
| Unit Size | Cost | Quantity | Stock |
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Product Info
| Cas No. | 195371-52-9 |
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| Purity | ≥98% |
| Formula | C23H24N2O |
| Formula Wt. | 344.46 |
| IUPAC Name | 2-Methyl-1-phenyl-4-(2-pyridinyl)-2-[2-(2-pyridinyl)ethyl]-1-butanone |
| Synonym | JAK2 inhibitor V, Z3 |
| Solubility | Soluble in DMSO or Ethanol |
Shipping and Storage
| Store Temp | -20°C |
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| Ship Temp | Ambient |
Downloads
| MSDS | |
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| Info Sheet | |
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References
Sayyah J, Magis A, Ostrov DA, et al. Z3, a novel Jak2 tyrosine kinase small-molecule inhibitor that suppresses Jak2-mediated pathologic cell growth. Mol Cancer Ther. 2008 Aug;7(8):2308-18. PMID: 18723478.