Description
JAK2 inhibitor V (Z3) is an inhibitor of JAK2 that exhibits anticancer activity. In erythroleukemia cells, this compound induces cell cycle arrest and suppresses cellular proliferation.
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JAK2 inhibitor V (Z3) is an inhibitor of JAK2 that exhibits anticancer activity. In erythroleukemia cells, this compound induces cell cycle arrest and suppresses cellular proliferation.
Cas No. | 195371-52-9 |
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Purity | ≥98% |
Formula | C23H24N2O |
Formula Wt. | 344.46 |
IUPAC Name | 2-Methyl-1-phenyl-4-(2-pyridinyl)-2-[2-(2-pyridinyl)ethyl]-1-butanone |
Synonym | JAK2 inhibitor V, Z3 |
Solubility | Soluble in DMSO or Ethanol |
Store Temp | -20°C |
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Ship Temp | Ambient |
MSDS | |
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Info Sheet | |
Brochures |
Sayyah J, Magis A, Ostrov DA, et al. Z3, a novel Jak2 tyrosine kinase small-molecule inhibitor that suppresses Jak2-mediated pathologic cell growth. Mol Cancer Ther. 2008 Aug;7(8):2308-18. PMID: 18723478.