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Scopolamine N-butylbromide

Scopolamine N-butylbromide

Product ID S1058
Cas No. 149-64-4
Purity ≥98%
Product Unit SizeCostQuantityStock
1 g $71.50 In stock
5 g $204.30 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Scopolamine is a tropane alkaloid found in Solanaceae family plants that exhibits antiemetic and anticholinergic activities. Scopolamine inhibits muscarinic acetylcholine receptors (mAChRs) with a moderate selectivity for M1 mAChRs. Scopolamine is used to induce cognitive deficits in animal models of Alzheimer’s disease. Additionally, scopolamine displays some antidepressant activity and has previously been used in the treatment of organophosphate poisoning.

Product Info

Cas No.

149-64-4

Purity

≥98%

Formula

C21H30BrNO4

Formula Wt.

440.38

IUPAC Name

[(1S,2S,4R,5R)-9-butyl-9-methyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonan-7-yl] (2S)-3-hydroxy-2-phenylpropanoate;bromide

Synonym

Amisepan, Buscolamin, N-Butylhyoscine bromide, Tirantil

Melting Point

143°C

Solubility

Soluble in water and methylene chloride

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

S1058 MSDS PDF

Info Sheet

S1058 Info Sheet PDF

References

Jung IH, Lee HE, Park SJ, et al. Ameliorating effect of spinosin, a C-glycoside flavonoid, on scopolamine-induced memory impairment in mice. Pharmacol Biochem Behav. 2014 May;120:88-94. PMID: 24582850.

Drevets WC, Zarate CA Jr, Furey ML. Antidepressant effects of the muscarinic cholinergic receptor antagonist scopolamine: a review. Biol Psychiatry. 2013 Jun 15;73(12):1156-63. PMID: 23200525.

Custom Order

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  • This field is for validation purposes and should be left unchanged.

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