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Levo-Chloramphenicol

Product ID C2845
Cas No. 56-75-7
Purity ≥98%
Product Unit SizeCostQuantityStock
5 g $45.00 In stock
10 g $65.00 In stock
50 g $125.00 In stock
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  • Description
  • Product Info
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Description

Chloramphenicol is an antibiotic compound that binds the 50S subunit of the bacterial ribosome, suppressing mitochondrial protein translation; it inhibits peptidyl transferase, preventing translocation. Chloramphenicol exhibits antibacterial activity against Streptomyces.

Product Info

Cas No.

56-75-7

Purity

≥98%

Formula

C11H12Cl2N2O5

Formula Wt.

323.13

Chemical Name

Acetamide, 2,2-dichloro-N-((1R,2R)-2-hydroxy-1- (hydroxymethyl)-2-(4-nitrophenyl)ethyl)-

IUPAC Name

2,2-dichloro-N-[(1R,2R)-1, 3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide

Synonym

Chloromyxin, Ophthochlor, Ophthocort.

Melting Point

150.5-151.5°C

Solubility

Soluble in methanol, ethanol or acetone.

Appearance

White or Yellowish-White Crystalline Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

C2845 MSDS PDF

Info Sheet

C2845 Info Sheet PDF

References

Sheth A, Escobar-Alvarez S, Gardner J, et al. Inhibition of human mitochondrial peptide deformylase causes apoptosis in c-myc-overexpressing hematopoietic cancers. Cell Death Dis. 2014 Mar 27;5:e1152. PMID: 24675470.

Rajesh T, Song E, Lee BR, et al. Increased sensitivity to chloramphenicol by inactivation of manB in Streptomyces coelicolor. J Microbiol Biotechnol. 2012 Oct;22(10):1324-9. PMID: 23075781.

Wilson DN. On the specificity of antibiotics targeting the large ribosomal subunit. Ann N Y Acad Sci. 2011 Dec;1241:1-16. PMID: 22191523.

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