| Product Unit Size | Cost | Quantity | Stock |
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LY287445 is an inhibitor of FGFR that exhibits anticancer chemotherapeutic activity. LY287445 inhibits cell proliferation and tumor growth across in vitro and in vivo models of several cancers, including lung cancer, gastric cancer, and multiple myeloma.
| Cas No. | 1254473-64-7 |
|---|---|
| Purity | ≥98% |
| Formula | C21H19Cl2N5O2 |
| Formula Wt. | 444.31 |
| IUPAC Name | 2-[4-[(E)-2-[5-[(1R)-1-(3,5-dichloropyridin-4-yl)ethoxy]-1H-indazol-3-yl]ethenyl]pyrazol-1-yl]ethanol |
| Solubility | DMSO 88 mg/mL (198.05 mM) Ethanol 57 mg/mL warmed (128.28 mM) Water Insoluble |
| Appearance | Off-white Powder |
| Store Temp | 4°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Zhao G, Li WY, Chen D, et al. A novel, selective inhibitor of fibroblast growth factor receptors that shows a potent broad spectrum of antitumor activity in several tumor xenograft models. Mol Cancer Ther. 2011 Nov;10(11):2200-10. PMID: 21900693.
