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LY-2874455

Product ID L9602
Cas No. 1254473-64-7
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $153.00 In stock
5 mg $412.00 In stock
10 mg $765.20 In stock
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  • Description
  • Product Info
  • Shipping and Storage
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  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

LY287445 is an inhibitor of FGFR that exhibits anticancer chemotherapeutic activity. LY287445 inhibits cell proliferation and tumor growth across in vitro and in vivo models of several cancers, including lung cancer, gastric cancer, and multiple myeloma.

Product Info

Cas No.

1254473-64-7

Purity

≥98%

Formula

C21H19Cl2N5O2

Formula Wt.

444.31

IUPAC Name

2-[4-[(E)-2-[5-[(1R)-1-(3,5-dichloropyridin-4-yl)ethoxy]-1H-indazol-3-yl]ethenyl]pyrazol-1-yl]ethanol

Solubility

DMSO 88 mg/mL (198.05 mM) Ethanol 57 mg/mL warmed (128.28 mM) Water Insoluble

Appearance

Off-white Powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

L9602 MSDS PDF

Info Sheet

L9602 Info Sheet PDF

References

Zhao G, Li WY, Chen D, et al. A novel, selective inhibitor of fibroblast growth factor receptors that shows a potent broad spectrum of antitumor activity in several tumor xenograft models. Mol Cancer Ther. 2011 Nov;10(11):2200-10. PMID: 21900693.

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