• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Notoginsenoside R1

Notoginsenoside R1

Product ID N5778
Cas No. 80418-24-2
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $93.80 In stock
5 mg $245.30 In stock
10 mg $408.30 In stock
25 mg $816.70 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Notoginsenoside R1 is a triterpene saponin originally found in species of Panax (ginseng) that exhibits neuroprotective, anti-atherosclerotic, anti-inflammatory, anti-hyperlipidemic, and immunostimulatory activities. Notoginsenoside R1 decreases amyloid-β-induced oxidative damage and MAPK signaling, improving cell viability in cellular models of Alzheimer’s disease. In ApoE knockout animals, notoginsenoside R1 increases expression of glutathione and superoxide dismutase and decreases expression of inflammatory cytokines; it also decreases LDL, triglyceride, and cholesterol levels and increases HDL levels, preventing atherosclerotic lesions. This compound also increases antigen-induced spleenocyte proliferation and IgG titers in vivo.

Product Info

Cas No.

80418-24-2

Purity

≥98%

Formula

C47H80O18

Formula Wt.

933.13

IUPAC Name

(2S,3R,4S,5S,6R)-2-[(2S)-2-[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-6-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxyoxan-2-yl]oxy-3,12-dihydroxy-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-methylhept-5-en-2-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol

Solubility

Soluble in DMSO.

Appearance

White Powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

N5778 MSDS PDF

Info Sheet

N5778 Info Sheet PDF

References

Ma B, Meng X, Wang J, et al. Notoginsenoside R1 attenuates amyloid-β-induced damage in neurons by inhibiting reactive oxygen species and modulating MAPK activation. Int Immunopharmacol. 2014 Jun 24;22(1):151-159. PMID: 24975829.

Jia C, Xiong M, Wang P, et al. Notoginsenoside R1 Attenuates Atherosclerotic Lesions in ApoE Deficient Mouse Model. PLoS One. 2014 Jun 16;9(6):e99849. PMID: 24933211.

Sun HX, Chen Y, Ye Y. Ginsenoside Re and notoginsenoside R1: Immunologic adjuvants with low haemolytic effect. Chem Biodivers. 2006 Jul;3(7):718-26. PMID: 17193304.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • G4796

    Glycerol Monolaurate

    Surfactant found in coconut oil.

    ≥98%
  • O4417

    Oleanolic Acid

    Triterpenoid found in Vigna angularis and Trigo...

    ≥98%
  • B5875

    Bosutinib, structural isomer

    Bosutinib isomer; Src and Abl inhibitor.

    ≥98%
  • B0108

    Bactenecin

    Cathelicidin derivative, antimicrobial peptide,...

    ≥95%
  • D604080

    DpC

    Anti-metastatic

    ≥99%
  • D582703

    Dorsomorphin

    Inhibitor of ALK2, ALK3, ALK6, and AMPK.

    ≥98%
  • S5746

    Solanesol

    All-trans nonaprenol isoprenoid, found in Solan...

    TLC≥95%
  • I8618

    Ivermectin

    Avermectin; glu-gated Cl- channel activator, Gl...

    ≥95%
  • E5358

    Enoxacin

    Fluoroquinolone; vacuolar H+ ATPase, topoisomer...

    ≥98%
  • E5241

    Met-Enkephalin

    Endogenous opioid peptide; δOR and μOR agonis...

    ≥95%
  • T1016

    Propyl Analog of Paclitaxel

    Fermentation impurity

    ≥95%
  • M1687

    Mevinolin

    Statin, naturally produced by mushrooms; HMG-Co...

    ≥97%
  • B1668

    Berteroin

    Thio sulforaphane analog, ITC.

    ≥97%
  • P1200

    PD-184352

    MEK1/2 and Raf inhibitor.

    ≥98%
  • E537334

    Enniatin B

    Mycotoxin contaminant found in cereal grains.

    ≥98%
  • G2969

    Growth Hormone Releasing Hexapeptide

    Synthetic peptide hormone, met-enkephalin analo...

    ≥95%
  • P6800

    Pravastatin Lactone

    Statin; HMG-CoA reductase inhibitor.

    ≥98%
  • F4556

    Florfenicol

    Synthetic fluorinated thiamphenicol analog; pro...

    ≥98%
  • P2304

    Phalloidin

    Phallotoxin found in Amanita phalloides; microt...

    ≥90%
  • D3215

    Didymin

    Flavonoid glycoside found in citrus fruit.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only