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Imatinib free base

Product ID I4800
Cas No. 152459-95-5 
Purity ≥99%
Product Unit SizeCostQuantityStock
25 mg $61.80 In stock
100 mg $123.60 In stock
500 mt $250.00 Please Inquire
500 mg $309.00 In stock
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  • Description
  • Product Info
  • Shipping and Storage
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  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Imatinib is an anticancer chemotherapeutic compound that inhibits Abl, c-Kit, and PDGFR; it is used clinically to treat Philadelphia chromosome-positive chronic myelogenous leukemia (CML) and acute lymphocytic leukemia (ALL). In cellular assays, imatinib accelerates erythroblast differentiation and inhibits melanogenesis.

Product Info

Cas No.

152459-95-5 

Purity

≥99%

Formula

C29H31N7O

Formula Wt.

493.62

Chemical Name

Imatinib

IUPAC Name

4-[(4-Methyl-1-piperazinyl)methyl]-N-(4-methyl-3-{[4-(3-pyridinyl)-2-pyrimidinyl]amino}phenyl)benzamide

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

I4800 MSDS PDF

Info Sheet

I4800 Info Sheet PDF

References

Wang Y, Zhao Y, Liu L, et al. Inhibitory effects of imatinib mesylate on human epidermal melanocytes. Clin Exp Dermatol. 2014 Mar;39(2):202-8. PMID: 24479586.

D'allard D, Gay J, Descarpentries C, et al. Tyrosine kinase inhibitors induce down-regulation of c-Kit by targeting the ATP pocket. PLoS One. 2013 Apr 23;8(4):e60961. PMID: 23637779.

Gambacorti-Passerini CB, Gunby RH, Piazza R, et al. Molecular mechanisms of resistance to imatinib in Philadelphia-chromosome-positive leukaemias. Lancet Oncol. 2003 Feb;4(2):75-85. PMID: 12573349.

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