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Melanin Concentrating Hormone, human/mouse/rat

Product ID M1646
Cas No. 128315-56-0
Purity ≥98%
Product Unit SizeCostQuantityStock
0.5 mg $220.30 In stock
1 mg $374.70 In stock
2.5 mg $661.60 In stock
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  • Description
  • Product Info
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Description

Melanin-concentrating hormone (MCH) is an endogenous peptide hormone that regulates energy homeostasis, feeding behavior, and circadian rhythms; it exhibits orexigenic and pro-inflammatory activities. MCH increases feeding behavior in animals and inhibits IL-10 expression, modulating inflammation. Increases in MCH expression are linked to irritable bowel syndrome (IBS).

Product Info

Cas No.

128315-56-0

Purity

≥98%

Formula

C105H160N30O26S4

Formula Wt.

2386.8

Synonym

MCH

Solubility

Soluble in water (1 mg/mL).

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

Info Sheet

M1646 Info Sheet PDF

References

Palomba M, Seke Etet PF, Veronesi C. Effect of inflammatory challenge on hypothalamic neurons expressing orexinergic and melanin-concentrating hormone. Neurosci Lett. 2014 Jun 6;570:47-52. PMID: 24708924.

Ziogas DC, Karagiannis AK, Geiger BM, et al. Inflammation-induced functional connectivity of melanin-concentrating hormone and IL-10. Peptides. 2014 May;55:58-64. PMID: 24556508.

Verret L, Goutagny R, Fort P, et al. A role of melanin-concentrating hormone producing neurons in the central regulation of paradoxical sleep. BMC Neurosci. 2003 Sep 9;4:19. PMID: 12964948.

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