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Chalcone

Product ID C2800
Cas No. 94-41-7
Purity ≥97%
Product Unit SizeCostQuantityStock
25 g $53.00 In stock
100 g $129.50 Please Inquire
500 g $341.40 Please Inquire
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  • Description
  • Product Info
  • Shipping and Storage
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  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Chalcone is an enone on which a variety of structures are based. Chalcone derivatives typically exhibit anti-inflammatory, antioxidative, neuroprotective, analgesic, anticancer, and anti-parasitic activities.

Product Info

Cas No.

94-41-7

Purity

≥97%

Formula

C15H12O

Formula Wt.

208.26

Chemical Name

1,3-Diphenyl-2-propen-1-one

IUPAC Name

(E)-1,3-diphenylprop-2-en-1-one

Synonym

Chalkone, trans-Benzylideneacetophenone

Melting Point

54-57°C

Solubility

Insoluble in water. Slightly soluble in ethanol.

Appearance

Light Yellow Crystal Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

C2800 MSDS PDF

Info Sheet

C2800 Info Sheet PDF

References

Wu JZ, Cheng CC, Shen LL, et al. Synthetic Chalcones with Potent Antioxidant Ability on H2O2-Induced Apoptosis in PC12 Cells. Int J Mol Sci. 2014 Oct 14;15(10):18525-18539. PMID: 25318055.

Jantan I, Bukhari SN, Adekoya OA, et al. Studies of synthetic chalcone derivatives as potential inhibitors of secretory phospholipase A2, cyclooxygenases, lipoxygenase and pro-inflammatory cytokines. Drug Des Devel Ther. 2014 Sep 16;8:1405-18. PMID: 25258510.

Abdellatif KR, Elshemy HA, Salama SA, et al. Synthesis, characterization and biological evaluation of novel 4'-fluoro-2'-hydroxy-chalcone derivatives as antioxidant, anti-inflammatory and analgesic agents. J Enzyme Inhib Med Chem. 2014 Sep 8:1-8. PMID: 25198887.

Karthikeyan C, Narayana Moorthy NS, Ramasamy S, et al. Advances in Chalcones with Anticancer Activities. Recent Pat Anticancer Drug Discov. 2014 Aug 19. [Epub ahead of print]. PMID: 25138130.

Shivahare R, Korthikunta V, Chandasana H, et al. Synthesis, structure-activity relationships, and biological studies of chromenochalcones as potential antileishmanial agents. J Med Chem. 2014 Apr 24;57(8):3342-57. PMID: 24635539.

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