| Product Unit Size | Cost | Quantity | Stock |
|---|
Etofenamate is a nonselective non-steroidal anti-inflammatory drug (NSAID) that prevents prostaglandin synthesis, likely through the inhibition of COX-1/2 and lipoxygenase; it exhibits analgesic and anti-inflammatory activities. In animal models of carrageenan-induced inflammation, etofenamate suppresses swelling and increases the pain threshold. Use of etofenamate is limited by drug-induced allergic contact dermatitis.
| Cas No. | 30544-47-9 |
|---|---|
| Purity | ≥98% |
| Formula | C18H18F3NO4 |
| Formula Wt. | 369.34 |
| IUPAC Name | 2-(2-Hydroxyethoxy)ethyl 2-{[3-(trifluoromethyl)phenyl]amino}benzoate |
| Solubility | 10 mM in DMSO |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Stratz T. Intramuscular etofenamate in the treatment of acute lumbago. Effectiveness and tolerance in comparison with intramuscular diclofenac-Na. Fortschr Med. 1990 Apr 30;108(13):264-6. PMID: 2142116.
Pelster B, Dell HD. Anti-inflammatory and analgesic activity of etofenamate after intramuscular injection in laboratory animals. Arzneimittelforschung. 1990 Mar;40(3):297-300. PMID: 2346539.
Nakamura H, Motoyoshi S, Ishii K, et al. The mode of anti-inflammatory action of a topical non-steroidal anti-inflammatory drug, etofenamate. Nihon Yakurigaku Zasshi. 1987 Jan;89(1):15-24. PMID: 2883093.
