• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Baccatin III

Baccatin III

Product ID T0095
Cas No. 27548-93-2
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $118.40 In stock
10 mg $234.70 In stock
25 mg $500.40 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Baccatin III is a diterpene found in Taxus and various fungal organisms that exhibits immunomodulatory and anticancer chemotherapeutic activities. Unlike most taxanes, baccatin III does not bind tubulin; it is primarily used in the synthesis of taxol. In animal models of breast cancer and colon cancer, baccatin III decreases tumor growth by suppressing accumulation of myeloid-derived suppressor cells. In other various cancer cell lines, this compound induces apoptosis and inhibits proliferation in a caspase 10-dependent manner. In bone marrow dendritic cells, baccatin III increases MHC class I and II antigen presentation; similarly, it increases cytotoxic T lymphocyte responses in vivo.

Product Info

Cas No.

27548-93-2

Purity

≥98%

Formula

C31H38O11

Formula Wt.

586.63

Chemical Name

7,11-Methano-5H-cyclodeca(3,4)benz(1,2-b)oxet-5-one-6,12b-bis(acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,- 9,10,11,12,12a,12b-dodecahydro-4,9,11-trihydroxy-4a,- 8,13,13-tetramethyl-,(2aR-(2aα,4β,4aβ,6β,9α,11α,12α,-12aα,12bα))-

IUPAC Name

[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-diacetyloxy-1,9,15-trihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate

Synonym

BACCATINE III

Melting Point

229-234°C

Solubility

Soluble in DMSO or ethanol. Insoluble in water.

Appearance

White to off white crystalline powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

T0095 MSDS PDF

Info Sheet

T0095 Info Sheet PDF

References

Lee YH, Lee YR, Park CS, et al. Baccatin III, a precursor for the semisynthesis of paclitaxel, inhibits the accumulation and suppressive activity of myeloid-derived suppressor cells in tumor-bearing mice. Int Immunopharmacol. 2014 Aug;21(2):487-93. PMID: 24957690.

Chakravarthi BV, Sujay R, Kuriakose GC, et al. Inhibition of cancer cell proliferation and apoptosis-inducing activity of fungal taxol and its precursor baccatin III purified from endophytic Fusarium solani. Cancer Cell Int. 2013 Oct 23;13(1):105. PMID: 24152585.

Lee YH, Lee YR, Kim KH, et al. Baccatin III, a synthetic precursor of taxol, enhances MHC-restricted antigen presentation in dendritic cells. Int Immunopharmacol. 2011 Aug;11(8):985-91. PMID: 21354357.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • T3034

    Thienylethyl Isothiocyanate

    Thienylbutyl ITC analog.

    ≥98%
  • W5727

    Wogonoside

    Flavonoid glycoside found in Scutellaria.

    ≥98%
  • P4492

    PLX4720

    V600E B-Raf inhibitor.

    ≥98%
  • C1620

    Ceftiofur Hydrochloride

    β-lactam; penicillin binding protein inhibitor...

    ≥90%
  • B4514

    Bleomycin A5 Hydrochloride Cu

    Induces apoptosis, DNA cleavage and strand brea...

    ≥85%
  • K7600

    KT5720

    PKA and PDK1 inhibitor, HCN channel blocker, po...

    ≥98%
  • T1754

    Tenatoprazole

    H+/K+ ATPase inhibitor.

    ≥98%
  • C0170

    N-(4-Carbethoxyphenyl)retinamide

    Retinoid, differentiation inducer.

    ≥98%
  • B560000

    RAD51 inhibitor, B02

    RAD51 inhibitor.

    ≥98%
  • G3556

    Ginsenoside Rg3

    Triterpene saponin found in species of Panax; Î...

    ≥98%
  • T0093

    2′-Acetyltaxol

    Taxane synthesis intermediate.

    ≥98%
  • A7868

    Atropine

    Tropane alkaloid found in plants in the Solanac...

    ≥98%
  • H1672

    Hesperetin

    Flavanone found in species of Citrus; L-type Ca...

    ≥97%
  • M721002

    MSA-2

    STING agonist

    ≥98%
  • F4679

    Flubendazole

    Benzimidazole; microtubule polymerization inhib...

    ≥98%
  • L5822

    Lofexidine Hydrochloride

    α2-adrenergic agonist.

    ≥98%
  • P2859

    Phosphate Acceptor Peptide

    PKC and S6 kinase substrate.

    ≥95%
  • B6805

    Bradykinin (1-7)

    Natriuretic, vasodilatory peptide fragment; B1/...

    ≥95%
  • L2876

    Luteinizing Hormone Releasing Hormone III, lamprey

    Peptide hormone found in eels; GnRH agonist, we...

    ≥98%
  • R5773

    Rosiglitazone

    Thiazolidinedione; PPARγ agonist.

    ≥99%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only