PF-06939999

Name: PF-06939999
SKU: P200099
Availability: InStock

Product ID P200099

Cas No. 2159123-14-3

Purity ≥98%

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Product Info
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References

Description

PF-06939999 is a SAM-competitve inhibitor of PRMT5.

Product Info

Cas No.	2159123-14-3
Purity	≥98%
Formula	C₂₂H₂₃F₃N₄O₃
Formula Wt.	448.45
IUPAC Name	(1S,2S,3S,5R)-3-[[6-(difluoromethyl)-5-fluoro-1,2,3,4-tetrahydroisoquinolin-8-yl]oxy]-5-(4-methylpyrrolo[2,3-d]pyrimidin-7-yl)cyclopentane-1,2-diol
Synonym	PF06939999; PRMT5-IN-3
Appearance	White to off white powder

Shipping and Storage

Store Temp	-20°C
Ship Temp	Ambient

Downloads

Info Sheet	P200099 Info Sheet PDF

References

Jensen-Pergakes K, Tatlock J, Maegley K, et al. SAM-competitive PRMT5 inhibitor PF-06939999 demonstrates antitumor activity in splicing dysregulated NSCLC with decreased liability of drug resistance. Mol Cancer Ther. 2022 Jan;21(1):3-15. PMID 34737197

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