• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Ginkgolide B

Ginkgolide B

Product ID G3355
Cas No. 15291-77-7
Purity ≥98%
Product Unit SizeCostQuantityStock
10 mg $92.00 In stock
25 mg $183.60 In stock
50 mg $347.00 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Ginkgolide B is a terpene lactone found in Ginkgo that exhibits anti-atherosclerotic, neuroprotective, neuromodulatory, antioxidative, and anti-inflammatory activities. Ginkgolide B inhibits ATP release from thrombin-activated platelets, downregulates expression of PF4 and CD40L, and decreases phosphorylation of Syk and p38 MAPK, suppressing platelet function in cellular models of atherosclerosis. In neurons, ginkgolide B protects against ischemic injury in a PI3K-dependent manner. Ginkgolide B also inhibits glycine receptors and increases activation of PKA, Ca2+ signaling, and glutamate release. In animal models of cerebral edema, this compound prevents edema and decreases levels of malondialdehyde, activated caspase 3, and PARP and increases levels of superoxide dismutase and glutathione.

Product Info

Cas No.

15291-77-7

Purity

≥98%

Formula

C20H24O10

Formula Wt.

424.40

IUPAC Name

8-tert-butyl-6,12,17-trihydroxy-16-methyl-2,4,14,19-tetraoxahexacyclo[8.7.2.01,11.03,7.07,11.013,17]nonadecane-5,15,18-trione

Melting Point

~300°C

Solubility

Insoluble in water. Soluble in DMSO, acetone, ethanol, ethyl acetate, methanol.

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

G3355 MSDS PDF

Info Sheet

G3355 Info Sheet PDF

References

Liu X, Yan Y, Bao L, et al. Ginkgolide B inhibits platelet release by blocking Syk and p38 MAPK phosphorylation in thrombin-stimulated platelets. Thromb Res. 2014 Sep 6. [Epub ahead of print]. PMID: 25223809.

Botao Y, Ma J, Xiao W, et al. Protective effect of ginkgolide B on high altitude cerebral edema of rats. High Alt Med Biol. 2013 Mar;14(1):61-4. PMID: 23537262.

Wu X, Qian Z, Ke Y, et al. Ginkgolide B preconditioning protects neurons against ischaemia-induced apoptosis. J Cell Mol Med. 2009 Nov-Dec;13(11-12):4474-83. PMID: 19602048.

Wang SJ, Chen HH. Ginkgolide B, a constituent of Ginkgo biloba, facilitates glutamate exocytosis from rat hippocampal nerve terminals. Eur J Pharmacol. 2005 May 9;514(2-3):141-9. PMID: 15910800.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • G4798

    Glycitein

    Aglycone isoflavone found in soy and red clover...

    ≥98%
  • L3455

    α-Linolenic Acid

    An omega-3 fatty acid.

    ≥98%
  • G2868

    Ghrelin, human

    Endogenous peptide hormone, involved in feeding...

    ≥98%
  • B3278

    Biotin

    Water-soluble coenzyme, vitamin (B7) found in v...

    ≥98%
  • D3357

    Diosmin

    Flavone found in Teucrium.

    ≥95%
  • C446176

    Clemastine Fumarate

    Antihistamine with potential neuroprotective ac...

    ≥99%
  • R3222

    Rifamycin SV Monosodium

    Ansamycin; bacterial DNA-dependent RNA polymera...

    ≥98%
  • L1735

    Levitide

    Antimicrobial peptide found in amphibians.

    ≥95%
  • B022691

    Baricitinib

    Selective and reversible JAK inhibitor.

    ≥99%
  • Q8019

    Quetiapine Fumarate

    5-HT1A and σ1/2 agonist, 5-HT2A/2C/6/7, D1-4, ...

    ≥99%
  • G3557

    Ginsenoside Rh1

    Triterpene saponin found in species of Panax.

    ≥77%
  • T1652

    Teniposide

    Podophyllotoxin derivative; topoisomerase II in...

    ≥97%
  • U6856

    Urocortin II, human

    Endogenous peptide, involved in stress signalin...

    ≥95%
  • F8151

    Fumonisin B3

    Mycotoxin produced by Fusarium fungi that infec...

    ≥98%
  • A4802

    Amantadine Hydrochloride

    Viral M2 proton channel blocker, MAO-A, NET, NM...

    ≥98%
  • P6855

    (±)-S-Propyl-L-cysteine-S-oxide

    Organosulfur found in Allium; analog of alliin....

    ≥98%
  • G4479

    Glucagon (19-29), human

    Endogenous peptide hormone, glugagon fragment; ...

    ≥95%
  • P4560

    Proteolipid Protein (139-151)

    Immunodominant peptide fragment of PLP, used to...

    ≥95%
  • L5769

    Lorglumide Sodium

    CCK antagonist.

    ≥98%
  • A4441

    Allicin, aqueous solution

    Organosulfur found in garlic; Kir K+ channel ac...

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only