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Atropine

Atropine

Product ID A7868
Cas No. 51-55-8
Purity ≥98%
Product Unit SizeCostQuantityStock
1 g $48.20 In stock
5 g $96.40 In stock
25 g $394.00 In stock
100 g $1,045.00 Please Inquire
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Atropine is a tropane alkaloid found in plants in the Solanaceae family. Atropine is an anticholinergic compound that also exhibits analgesic and antinociceptive activities. Atropine is a competitive inhibitor of muscarinic acetylcholine receptors (mAChRs) that is commonly used for ophthalmic treatments such as initiating mydriasis. Atropine displays cardiostimulatory/positive inotropic activity as well, increasing heart rate by inhibiting vagal nerve activity. In animal models of thermal pain, atropine exhibits analgesic activity; in other animal models, atropine inhibits histamine-induced increases in thromboxane A2 (TxA2) levels.

Product Info

Cas No.

51-55-8

Purity

≥98%

Formula

C17H23NO3

Formula Wt.

289.37

IUPAC Name

[(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate

Synonym

(±)-Hyoscyamine, Tropine tropate, Tropyl tropate

Solubility

16mg/mi in ethanol 10mg/ml in DMSO 2mg/ml in DMF

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

A7868 MSDS PDF

Info Sheet

A7868 Info Sheet PDF

References

Ghelardini C, Malmberg-Aiello P, Giotti A, et al. Investigation into atropine-induced antinociception. Br J Pharmacol. 1990 Sep;101(1):49-54. PMID: 2282466.

Alberts P, Ogren VR. Interaction of forskolin with the effect of atropine on [3H]acetylcholine secretion in guinea-pig ileum myenteric plexus. J Physiol. 1988 Jan;395:441-53. PMID: 2457681.

Berti F, Folco GC, Giachetti A, et al. Atropine inhibits thromboxane A2 generation in isolated lungs of the guinea-pig. Br J Pharmacol. 1980 Mar;68(3):467-72. PMID: 7052339.

Custom Order

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