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Endomorphin-1

Endomorphin-1

Product ID E5210
Cas No. 189388-22-5
Purity ≥95%
Product Unit SizeCostQuantityStock
5 mg $105.00 In stock
10 mg $210.00 In stock
25 mg $420.00 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Endomorphin-1 is an endogenous agonist at μ-opioid receptors (μORs) in the spinal cord; it exhibits antinociceptive/analgesic, immunosuppressive, and pro-angiogenic activities. Endomorphin-1 increases pain thresholds in animal models of thermal pain and inhibits the formation of antibodies in other cellular models. In HUVECs, this peptide stimulates proliferation, migration, adhesion, and tube formation.

Product Info

Cas No.

189388-22-5

Purity

≥95%

Formula

C34H38N6O5

Formula Wt.

610.72

IUPAC Name

(2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]-N-[(2S)-1-[[(2S)-1- amino-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2- yl]pyrrolidine-2-carboxamide

Solubility

Soluble in water (0.6 mg/mL), DMSO.

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

E5210 MSDS PDF

Info Sheet

E5210 Info Sheet PDF

References

Dai X, Song HJ, Cui SG, et al. The stimulative effects of endogenous opioids on endothelial cell proliferation, migration and angiogenesis in vitro. Eur J Pharmacol. 2010 Feb 25;628(1-3):42-50. PMID: 19932695.

Anton B, Leff P, Calva JC, et al. Endomorphin 1 and endomorphin 2 suppress in vitro antibody formation at ultra-low concentrations: anti-peptide antibodies but not opioid antagonists block the activity. Brain Behav Immun. 2008 Aug;22(6):824-32. PMID: 18374539.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

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