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Doxofylline

Product ID D5792
Cas No. 69975-86-6
Purity ≥98%
Product Unit SizeCostQuantityStock
250 mg $50.00 In stock
1 g $93.00 In stock
5 g $225.00 In stock
25 g $450.00 In stock
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  • Description
  • Product Info
  • Shipping and Storage
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  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Doxofylline is a xanthine derivative that inhibits phosphodiesterases (PDEs), but does not activate adenosine receptors. Doxofylline exhibits anti-asthma, anti-tussive, and bronchodilatory activities and is clinically used to treat asthma.

Product Info

Cas No.

69975-86-6

Purity

≥98%

Formula

C11H14N4O4

Formula Wt.

266.25

Chemical Name

7-(1,3-Dioxolan-2-yl-methyl)-3,7-dihydro-1,3- dimethyl-1H-purine-2,6-dione

IUPAC Name

7-(1,3-dioxolan-2-ylmethyl)-1,3-dimethylpurine-2,6-dione

Synonym

Ansimar, Maxivent, Ventax

Melting Point

144-145.5°C

Solubility

Soluble in water, acetone, ethyl acetate, hot methanol, hot ethanol, benzene or chloroform.

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

D5792 MSDS PDF

Info Sheet

D5792 Info Sheet PDF

References

Shukla D, Chakraborty S, Singh S, et al. Doxofylline: a promising methylxanthine derivative for the treatment of asthma and chronic obstructive pulmonary disease. Expert Opin Pharmacother. 2009 Oct;10(14):2343-56. PMID: 19678793.

Cirillo R, Barone D, Franzone JS. Doxofylline, an antiasthmatic drug lacking affinity for adenosine receptors. Arch Int Pharmacodyn Ther. 1988 Sep-Oct;295:221-37. PMID: 3245738.

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