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Tosufloxacin Tosylate

Tosufloxacin Tosylate

Product ID T5672
Cas No. 115964-29-9
Purity ≥98%
Product Unit SizeCostQuantityStock
100 mg $71.50 In stock
500 mg $163.40 In stock
1 g $306.20 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Tosufloxacin is a fluoroquinolone antibiotic that exhibits antibacterial efficacy in ocular infections and against Mycoplasma. Tosufloxacin inhibits bacterial DNA gyrase and topoisomerase IV.

Product Info

Cas No.

115964-29-9

Purity

≥98%

Formula

C19H15F3N4O3 • C7H8O3S

Formula Wt.

576.55

Chemical Name

7-(3-Amino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6- fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3- carboxylic acid toluenesulfonate

IUPAC Name

7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1, 8-naphthyridine-3-carboxylic acid;4-methylbenzenesulfonic acid

Synonym

Tosufloxacin toluenesulfonate, Ozex, Tosuxacin

Melting Point

258-260°C

Solubility

Very slighlty soluble in water.

Appearance

Yellowish crystalline powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

T5672 MSDS PDF

Info Sheet

T5672 Info Sheet PDF

References

Akaike H, Miyashita N, Kubo M, et al. In vitro activities of 11 antimicrobial agents against macrolide-resistant Mycoplasma pneumoniae isolates from pediatric patients: results from a multicenter surveillance study. Jpn J Infect Dis. 2012;65(6):535-8. PMID: 23183207.

Ayaki M, Iwasawa A, Soda M, et al. Cytotoxicity of five fluoroquinolone and two nonsteroidal anti-inflammatory benzalkonium chloride-free ophthalmic solutions in four corneoconjunctival cell lines. Clin Ophthalmol. 2010 Sep 20;4:1019-24. PMID: 20922036.

Tanaka M, Onodera Y, Uchida Y, et al. Inhibitory activities of quinolones against DNA gyrase and topoisomerase IV purified from Staphylococcus aureus. Antimicrob Agents Chemother. 1997 Nov;41(11):2362-6. PMID: 9371334.

Custom Order

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