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Pancuronium Bromide

Pancuronium Bromide

Product ID P0252
Cas No. 15500-66-0
Purity ≥98%
Product Unit SizeCostQuantityStock
10 mg $98.60 In stock
50 mg $324.00 In stock
100 mg $563.60 In stock
250 mg $1,056.50 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Pancuronium is a reversible, competitive inhibitor of post-synaptic nicotinic acetylcholine receptors (nAChRs) that acts as a non-depolarizing neuromuscular junction (NMJ) blocker. When used clinically, pancuronium induces skeletal muscle relaxation and acts as an anesthetic.

Product Info

Cas No.

15500-66-0

Purity

≥98%

Formula

C35H60Br2N2O4

Formula Wt.

732.67

Chemical Name

1,1'-(3,17-Bis(acetyloxy)androstane-2,16-diyl)bis(1-methylpiperidinium) dibromide

IUPAC Name

[(2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-17-acetyloxy-10,13-dimethyl-2, 16-bis(1-methylpiperidin-1-ium-1-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16, 17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate;dibromide

Synonym

5alpha-Androstan-3alpha, 17beta-diol, 2beta16beta-dipipecolinio-, dibromide, diacetate

Melting Point

214-217C

Solubility

0.1 g/ml H2O clear, colorless

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

P0252 MSDS PDF

Info Sheet

P0252 Info Sheet PDF

References

Johnson PN, Miller J, Gormley AK. Continuous-infusion neuromuscular blocking agents in critically ill neonates and children. Pharmacotherapy. 2011 Jun;31(6):609-20. PMID: 21923445.

Jonsson M, Gurley D, Dabrowski M, et al. Distinct pharmacologic properties of neuromuscular blocking agents on human neuronal nicotinic acetylcholine receptors: a possible explanation for the train-of-four fade. Anesthesiology. 2006 Sep;105(3):521-33. PMID: 16931985.

Motamed C, Kirov K, Lieutaud T, et al. The mechanism of pancuronium potentiation of mivacurium block: use of the isolated-arm technique. Anesth Analg. 2000 Sep;91(3):732-5. PMID: 10960409.

Custom Order

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