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Ethisterone is a synthetic progestogen steroid hormone. Ethisterone was the first orally bioavailable progestin hormone used as a contraceptive but has since been replaced by newer hormones. Ethisterone has been used to make derivatives of anti-androgenic conjugates that inhibit cell growth in various models of prostate cancer.
| Cas No. | 434-03-7 |
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| Purity | ≥98% |
| Formula | C21H28O2 |
| Formula Wt. | 312.45 |
| Chemical Name | 17α-Hydroxypregn-4-en-20-yn-3-one |
| IUPAC Name | (8R,9S,10R,13S,14S,17R)-17-ethynyl-17-hydroxy-10,13-dimethyl-2,6,7,8,9, 11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one |
| Synonym | Lutocyclin, Ora-Lutin, Progestoral, Trosinone |
| Melting Point | 269-275°C |
| Solubility | Slightly soluble in alcohol, acetone, ether, and chloroform. Practically insoluble in water. |
| Appearance | Off-white crystalline powder |
| Store Temp | Ambient |
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| Ship Temp | Ambient |
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| Info Sheet |
Levine PM, Imberg K, Garabedian MJ, et al. Multivalent peptidomimetic conjugates: a versatile platform for modulating androgen receptor activity. J Am Chem Soc. 2012 Apr 25;134(16):6912-5. PMID: 22509763.
Forinash AB, Evans SL. New hormonal contraceptives: a comprehensive review of the literature. Pharmacotherapy. 2003 Dec;23(12):1573-91. PMID: 14695038.