• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
A-803467

A-803467

Product ID A0001
Cas No. 944261-79-4
Purity ≥97%
Product Unit SizeCostQuantityStock
10 mg $126.50 In stock
50 mg $438.80 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

A-803467 is a blocker of Nav1.8 (SCN10A) Na+ channels that exhibits antinociceptive and antiarrhythmic activities; it may also block Nav1.5 (SCN5A) Na+ channels. A-803467 inhibits mechanical and thermal pain nociception in vivo. This compound also blocks cardiac Na+ currents and alters action potential morphology in ventricular myocytes.

Product Info

Cas No.

944261-79-4

Purity

≥97%

Formula

C19H16ClNO4

Formula Wt.

357.79

Chemical Name

5-(4-Chlorophenyl)-N-(3,5-dimethoxyphenyl)-2-furamide

IUPAC Name

5-(4-Chlorophenyl)-N-(3,5-dimethoxyphenyl)-2-furamide

Solubility

DMSO 72 mg/mL Ethanol 11 mg/mL Water Insoluble

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

A0001 MSDS PDF

Info Sheet

A0001 Info Sheet PDF

References

Rahman W, Dickenson AH. Osteoarthritis-dependent changes in antinociceptive action of Nav1.7 and Nav1.8 sodium channel blockers: An in vivo electrophysiological study in the rat. Neuroscience. 2015 Jun 4;295:103-16. PMID: 25818052.

Han Z, Jiang Y, Xiao F, et al. The effects of A-803467 on cardiac Nav1.5 channels. Eur J Pharmacol. 2015 May 5;754:52-60. PMID: 25701724.

Liu XD, Yang JJ, Fang D, et al. Functional upregulation of Nav1.8 sodium channels on the membrane of dorsal root Ganglia neurons contributes to the development of cancer-induced bone pain. PLoS One. 2014 Dec 11;9(12):e114623. PMID: 25503076.

Qi B, Wei Y, Chen S, et al. Nav1.8 channels in ganglionated plexi modulate atrial fibrillation inducibility. Cardiovasc Res. 2014 Jun 1;102(3):480-6. PMID: 24419303.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • M3584

    Mivacurium

    Non-depolarizing NMJ blocker; nAChR antagonist....

    ≥98%
  • N3225

    Nigericin Sodium

    Polyether cationic ionophore.

    ≥98%
  • H9803

    Hyaluronic Acid Sodium (0.2 -5 kDA)

    Glycosaminoglycan

  • M184770

    4-O-Methylhonokiol

    Found in Magnolia officinalis.

    ≥98%
  • R3205

    Ribavirin

    Purine nucleoside analog; DNA chain terminator....

    ≥98%
  • S1971

    Sertraline Hydrochloride

    FIASMA, SERT and DAT inhibitor, α1-adrenergic ...

    ≥98%
  • O6845

    Orlistat

    Fatty acid synthase inhibitor.

    ≥98%
  • A5030

    4-Aminophenylphosphate Monosodium

    Alkaline phosphatase substrate used to quantify...

    ≥97%
  • A7461

    Asperosaponin VI

    Triterpene saponin found in Dipsacus asper.

    ≥98%
  • C0016

    Caerulomycin A

    Bipyridamine toxin.

    ≥96%
  • C0254

    Candesartan Celexetil Ester

    AT1 inhibitor.

    ≥98%
  • C9200

    CX-6258

    Pim kinase inhibitor.

    ≥98%
  • B5875

    Bosutinib, structural isomer

    Bosutinib isomer; Src and Abl inhibitor.

    ≥98%
  • P6004

    PP-242

    Dual mTORC1/mTORC2 inhibitor.

    ≥98%
  • S6131

    N,N-Dimethyl-Sphingosine

    PP2A activator, Sphk1 and PKC inhibitor.

    ≥98%
  • A5132

    Amikacin Disulfate

    Aminoglycoside; protein translation inhibitor.<...

    ≥98%
  • I524088

    Incensol Acetate

    Component of Frankincense resin.

    ≥98%
  • C1632

    Cefotaxime Acid

    β-lactam cephalosporin; penicillin binding pro...

    ≥91%
  • O9322

    Oxfendazole

    Benzimidazole; microtubule polymerization inhib...

    ≥98%
  • E6398

    EPZ-5676

    DOT1L HMT inhibitor.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only