Fenbendazole is a benzimidazole anti-parasitic/anti-helminthic that is used in veterinary medicine to treat infections of Giardia, Strongyloides, and various worms. Fenbendazole binds fungal tubulin, preventing microtubule polymerization and inhibiting hyphal growth and nuclear division.
| Cas No. | 43210-67-9 |
|---|---|
| Purity | ≥98% |
| Formula | C15H13N3O2S |
| Formula Wt. | 299.35 |
| Chemical Name | [5-(Phenylthio)-1H-benzimidazol-2-yl]carbamic acid methyl ester |
| IUPAC Name | methyl N-(6-phenylsulfanyl-1H-benzimidazol-2-yl)carbamate |
| Synonym | HOE-881v, Panacur, SafeGard |
| Melting Point | 233°C (dec) |
| Solubility | Insoluble in water. Slightly soluble in most organic solvents. Soluble in DMSO. |
| Appearance | A white or almost white crystalline powder |
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Küster T, Stadelmann B, Aeschbacher D, et al. Activities of fenbendazole in comparison with albendazole against Echinococcus multilocularis metacestodes in vitro and in a murine infection model. Int J Antimicrob Agents. 2014 Apr;43(4):335-42. PMID: 24646943.
Lubega GW, Prichard RK. Specific interaction of benzimidazole anthelmintics with tubulin: high-affinity binding and benzimidazole resistance in Haemonchus contortus. Mol Biochem Parasitol. 1990 Jan 15;38(2):221-32. PMID: 2325707.
Prichard RK. Anthelmintics for cattle. Vet Clin North Am Food Anim Pract. 1986 Jul;2(2):489-501. PMID: 3488116.
