• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
E-JIB-04

E-JIB-04

Product ID J3204
Cas No. 199596-05-9
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $118.00 In stock
25 mg $405.20 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

E-JIB-04 is the E stereoisomer of JIB-04, an inhibitor of Jumonji family histone demethylases; it does not inhibit activity of α-ketoglutarate. JIB-04 exhibits anticancer chemotherapeutic activity, inhibiting protein translation initiation. In cancer models, JIB-04 inhibits cell viability, decreases tumor burden, and increases survival rates.

Product Info

Cas No.

199596-05-9

Purity

≥98%

Formula

C17H13ClN4

Formula Wt.

308.77

Chemical Name

(E)-N-(5-Chloro-pyridin-2-yl)-N′-(phenyl-pyridin-2-yl-methylene)-hydrazine

IUPAC Name

5-Chloro-2-{(2E)-2-[phenyl(2-pyridinyl)methylene]hydrazino}pyridine

Synonym

NSC 693627, JHDM inhibitor VII

Solubility

DMSO 25 mg/mL Water Insoluble Ethanol Insoluble

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

J3204 MSDS PDF

Info Sheet

J3204 Info Sheet PDF

References

Van Rechem C, Black JC, Boukhali M, et al. Lysine demethylase KDM4A associates with translation machinery and regulates protein synthesis. Cancer Discov. 2015 Mar;5(3):255-63. PMID: 25564516.

Wang L, Chang J, Varghese D, et al. A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth. Nat Commun. 2013;4:2035. Erratum in: Nat Commun. 2013;4:2639. PMID: 23792809.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • H9801

    Hyaluronic Acid Sodium (~1,000,000)

    Endogenous anionic non-sulfated glycosaminoglyc...

  • I5215

    Indolicidin

    Antimicrobial peptide.

    ≥95%
  • S8009

    Substance P (7-11)

    Endogenous tachykinin peptide, involved in infl...

    ≥95%
  • G0245

    Gallocatechin Gallate

    Polyphenol found in Camilla sinensis; HIV integ...

    ≥98%
  • N1978

    Neurokinin B

    Neuromodulator, biomarker

    ≥95%
  • T6817

    D(+)-Trehalose Dihydrate

    α-Linked disaccharide composed of α-glucose u...

    ≥98%
  • C4000

    CK-636

    Arp2/3 inhibitor.

    ≥98%
  • L1869

    Lercanidipine Hydrochloride

    Calcium channel blocker.

    ≥98%
  • A044176

    Abemaciclib

    CDK inhibitor.

    ≥98%
  • E5477

    Entinostat

    Benzamide; HDAC1 inhibitor.

    ≥98%
  • M9608

    Myclobutanil

    14-α demethylase inhibitor.

    ≥97%
  • R1879

    Retinyl Palmitate

    Vitamin A derivative, palmitic acid ester of re...

    ≥1.70 MIU/g, bio assay
  • C0265

    Carnosic Acid

    Diterpene found in Rosmarinus.

    ≥98%
  • R7680

    Recombinant M. Tuberculosis Antigen TB 38+6+10

    Tuberculosis antigen

  • R2512

    RGD

    Tripeptide, binds cell surface integrins.

    ≥95%
  • A5031

    4-Aminophenylphosphate Disodium

    Alkaline phosphatase substrate used to quantify...

    ≥98%
  • A0101

    4-bromo-A23187

    Non-fluorescent halogenated A23187 analog, Ca2+...

    ≥98%
  • Z3444

    Zileuton

    5-Lipoxygenase inhibitor.

    ≥98%
  • D1731

    15,16-Dehydrocafestol

    Diterpene found in roasted coffee.

    ≥98%
  • O4532

    Oligomycin B

    Macrolide; F1F0 ATP synthase inhibitor.

    ≥97%, TLC, HPLC

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only