Description
Dacarbazine is an alkylator that attaches alkyl groups to purine bases on DNA; it exhibits anticancer chemotherapeutic activity. Dacarbazine is clinically used to treat various forms of cancer.
Product Info
| Cas No. | 4342-03-4 |
|---|---|
| Purity | ≥98% |
| Formula | C6H10N6O |
| Formula Wt. | 182.18 |
| Chemical Name | 5-(3,3-Dimethyl-1-triazenyl)-1H-imidazole-4- carboxamide |
| IUPAC Name | (5E)-5-(dimethylaminohydrazinylidene)imidazole-4-carboxamide |
| Synonym | Dacatic, DTIC-Dome, Deticene |
| Melting Point | 205°C |
| Solubility | Slightly soluble in water and alcohol. |
| Appearance | Light pink powder |
Shipping and Storage
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
Downloads
| MSDS | |
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| Info Sheet |
References
Gallamini A, Di Raimondo F, La Nasa G, et al. Standard therapies versus novel therapies in Hodgkin lymphoma. Immunol Lett. 2013 Sep-Oct;155(1-2):56-9. PMID: 24140162.
Koprowska K, Czyż M. Dacarbazine, a chemotherapeutic against metastatic melanoma and a reference drug for new treatment modalities. Postepy Hig Med Dosw (Online). 2011 Nov 23;65:734-51. PMID: 22173438.