LKT Labs

Biochemicals for Life Science Research

Delta Sleep Inducing Peptide

Product ID D1643
Cas No. 62568-57-4
Purity ≥95%
Product Unit SizeCostQuantityStock
1 mg $74.10 In stock
2 mg $126.00 In stock
5 mg $222.50 In stock
Bulk Quote

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Description

Delta sleep-inducing peptide exhibits anticonvulsant/antiepileptic and neuromodulatory activities. In vivo, this peptide decreases the incidence, severity, and duration of metaphit-induced seizures. Delta sleep-inducing peptide potentiates GABA currents and inhibits potentiation of NMDA currents in vivo. Additionally, this peptide exhibits hypoglycemia-like properties in other animal models, inhibiting non-enzymatic glycosylation of hemoglobin and decreasing protein oxidation. In myoleukemia cells, delta sleep-inducing peptide decreases expression of HSP70.

Product Info

Cas No.

62568-57-4

Purity

≥95%
Formula

C35H48N10O15
Formula Wt.

848.83
IUPAC Name

2-[[2-[[2-[2-[[2-[[2-[[2-[2-[[2-amino-3-(1H-indol-3-yl)propanoyl]amino]propanoylamino]acetyl]amino]acetyl]amino]-3-carboxypropanoyl]amino]propanoylamino]-3-hydroxypropanoyl]amino]acetyl]amino]pentanedioic acid
Solubility

Soluble in water.

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

D1643 MSDS PDF
Info Sheet

D1643 Info Sheet PDF

References

Bondarenko TI, Sorokina IA, Mayboroda EA, et al. Effect of delta sleep-inducing peptide on oxidative modification of proteins in rat tissues and blood during physiological aging. Bull Exp Biol Med. 2012 Jul;153(3):371-4. PMID: 22866315.

Nurbakov AA, Mikhaleva II, Sapozhnikov AM. Effect of delta-sleep-inducing peptide on expression of heat shock protein 70 kDa in K562 cells. Bull Exp Biol Med. 2009 Jan;147(1):39-41. PMID: 19526126.

Grigor'ev VV, Ivanova TA, Kustova EA, et al. Effects of delta sleep-inducing peptide on pre- and postsynaptic glutamate and postsynaptic GABA receptors in neurons of the cortex, hippocampus, and cerebellum in rats. Bull Exp Biol Med. 2006 Aug;142(2):186-8. PMID: 17369935.

Stanojlović OP, Zivanović DP, Mirković SD, et al. Antiepileptic activity of delta sleep-inducing peptide and its analogue in metaphit-provoked seizures in rats. Seizure. 2005 Jun;14(4):240-7. PMID: 15911358.

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