• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Regorafenib Anhydrous

Regorafenib Anhydrous

Product ID R1627
Cas No. 755037-03-7
Purity ≥99%
Product Unit SizeCostQuantityStock
1 mg $47.80 In stock
5 mg $61.40 In stock
25 mg $102.30 In stock
100 mg $258.90 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Regorafenib is an orally bioavailable multikinase inhibitor. This compound is clinically used in the treatment of metastatic colorectal cancer and non-responsive gastrointestinal stromal tumors. Regorafenib displays anticancer chemotherapeutic and anti-angiogenic properties, selective primarily for VEGFR2 but also displaying inhibitory activity against TIE2, VEGFR1/3, PDGFR-β, FGFR1, c-Kit, RET, and B-Raf.

Product Info

Cas No.

755037-03-7

Purity

≥99%

Formula

C21H15ClF4N4O3

Formula Wt.

482.82

Chemical Name

Regorafenib

IUPAC Name

4-[4-({[4-Chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide

Synonym

BAY73-4506

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

R1627 MSDS PDF

Info Sheet

R1627 Info Sheet PDF

References

Abou-Elkacem L, Arns S, Brix G, et al. Regorafenib inhibits growth, angiogenesis, and metastasis in a highly aggressive, orthotopic colon cancer model. Mol Cancer Ther. 2013 Jul;12(7):1322-31. PMID: 23619301.

Wilhelm SM, Dumas J, Adnane L, et al. Regorafenib (BAY 73-4506): a new oral multikinase inhibitor of angiogenic, stromal and oncogenic receptor tyrosine kinases with potent preclinical antitumor activity. Int J Cancer. 2011 Jul 1;129(1):245-55. PMID: 21170960.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • M4455

    MLN-2238

    Proteasome inhibitor, miR33b modulator.

    ≥95%
  • P6977

    Pyr-GR-pNA

    Fluorogenic substrate used to measure serine pr...

    ≥98%
  • M9356

    Myomodulin

    Proton pump inhibitor

    ≥95%
  • E537335

    Enniatin B1

    Mycotoxin contaminant found in cereal grains.

    ≥98%
  • M7528

    α-Melanocyte Stimulating Hormone

    Endogenous peptide hormone derived from POMC, i...

    ≥98%
  • S2957

    Shogaol

    Phenol found in Zingiber; PPARγ agonist, 5-HT3...

    ≥98%
  • B1655

    S-(N-Benzylthiocarbamoyl)-L-cysteine

    Cysteine conjugate of benzyl isothiocyanate (BI...

    ≥98%
  • W4096

    WKYMVM-NH2

    Synthetic peptide; FPRL1 agonist.

    ≥95%
  • C0145

    Calcitriol

    Active form of vitamin D, regulates dietary Ca2...

    ≥97%
  • H174466

    Helvolic acid

    A fungal metabolite that inhibits protein synth...

    ≥98%
  • A9712

    AZD-6482

    p110β PI3K inhibitor.

    ≥98%
  • C0368

    Carveol

    Terpene alcohol found in spearmint oil; TRPV3 a...

    ≥99%
  • P3313

    Pidotimod

    Immunostimulator, adjuvant.

    ≥98%
  • P1845

    Pelitinib

    EGFR inhibitor.

    ≥98%
  • H9714

    L-5-Hydroxytryptophan

    Endogenous amino acid, precursor of 5-HT and me...

    ≥98%
  • I611325

    IPI-549

    Selective inhibitor of the γ isoform of PI3K (...

    ≥98%
  • G1651

    Geniposidic Acid

    Iridoid glucoside found in Eucommia, Castilleja...

    ≥98%
  • S0133

    Saikosaponin C

    Triterpene saponin found in Bupleurum.

    ≥98%
  • O2145

    Ofloxacin Hydrochloride

    Fluoroquinolone; topoisomerase IV and bacterial...

    ≥98%
  • C9612

    Cyclosporin C

    Cyclosporin metabolite; weak calmodulin inhibit...

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only