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Acepromazine Maleate

Product ID A0916
Cas No. 3598-37-6
Purity ≥99%
Product Unit SizeCostQuantityStock
25 mg $120.30 In stock
100 mg $231.50 In stock
250 mg $370.40 In stock
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  • Description
  • Product Info
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Description

Acepromazine is a phenothiazine derivative antipsychotic agent related to chlorpromazine. Acepromazine maleate is primarily used in veterinary field as a sedative and antiemetic, although it has previously been used as an antipsychotic in humans. Acepromazine acts as an antagonist at D1/2 and 5-HT1A/2A receptors; it prevents sudden cardiac death in animal models of status epilepticus and reduces vasopressor activity of dopamine during anesthesia. Acepromazine may also inhibit ABCG2, a transport protein whose overexpression in tumors is associated with drug resistance.

Product Info

Cas No.

3598-37-6

Purity

≥99%

Formula

C19H22N2OS • C4H4O4

Formula Wt.

442.53

IUPAC Name

1-[10-[3-(dimethylamino)propyl]phenothiazin-2-yl]ethanone

Solubility

Water (>10 mg/mL)

Appearance

Yellow crystals

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

A0916 MSDS PDF

Info Sheet

A0916 Info Sheet PDF

References

Monteiro ER, Teixeira Neto FJ, et al. Effects of acepromazine on the cardiovascular actions of dopamine in anesthetized dogs. Vet Anaesth Analg. 2007 Sep;34(5):312-21. PMID: 17686118.

Harrigan T, Bureau YR, Persinger MA, et al. Prevention of sudden cardiac death by the atypical neuroleptic acepromazine following status epilepticus in rats. Life Sci. 1994;54(24):PL457-62. PMID: 8196501.

Wirth W, Goesswald R, Vater W. On the pharmacology of acylated phenothiazine derivatives. Arch Int Pharmacodyn Ther. 1959 Dec 1;123:78-114. PMID: 13845370.

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