• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Azelastine Hydrochloride

Azelastine Hydrochloride

Product ID A9818
Cas No. 79307-93-0
Purity ≥98%
Product Unit SizeCostQuantityStock
100 mg $114.70 In stock
500 mg $324.90 In stock
1 g $515.90 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Azelastine is a second generation antihistamine that inhibits H1 histamine receptors. Azelastine exhibits anti-allergic, anti-inflammatory, and anti-tussive activities and is clinically used to treat allergic rhinitis. Azelastine activates transient receptor potential vanilloid 1 (TRPV1) channels, inducing desensitization. In mast cells, azelastine inhibits production of TNF-α, IL-6, and IL-8 and suppresses activation of NF-κB. Additionally, this compound decreases capsaicin-induced cough in vivo.

Product Info

Cas No.

79307-93-0

Purity

≥98%

Formula

C22H23N3O • HCl

Formula Wt.

418.35

Chemical Name

4-[(4-Chlorophenyl)methyl]-2-(hexahydro-1-methyl- 1H-azepin-4-yl)-1(2H)-phthalazinone hydrochloroide

IUPAC Name

4-[(4-chlorophenyl)methyl]-2-(1-methylazepan-4-yl)phthalazin-1-one; hydrochloride

Synonym

Allergodil, Astelin, Azeptin, Optilast, Rhinolast

Melting Point

225-229°C

Solubility

Slightly soluble in ethanol, octanol or glycerine.

Appearance

White Crystalline Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

A9818 MSDS PDF

Info Sheet

A9818 Info Sheet PDF

References

Singh U, Bernstein JA, Haar L, et al. Azelastine desensitization of transient receptor potential vanilloid 1: A potential mechanism explaining its therapeutic effect in nonallergic rhinitis. Am J Rhinol Allergy. 2014 May;28(3):215-24. PMID: 24980233.

Horak F, Zieglmayer UP. Azelastine nasal spray for the treatment of allergic and nonallergic rhinitis. Expert Rev Clin Immunol. 2009 Nov;5(6):659-69. PMID: 20477689.

Kempuraj D, Huang M, Kandere-Grzybowska K, et al. Azelastine inhibits secretion of IL-6, TNF-alpha and IL-8 as well as NF-kappaB activation and intracellular calcium ion levels in normal human mast cells. Int Arch Allergy Immunol. 2003 Nov;132(3):231-9. PMID: 14646384.

Ito N, Shioya T, Watanabe A, et al. Mechanism of the antitussive effect of azelastine in guinea pigs. Arzneimittelforschung. 2002;52(6):441-7. PMID: 12109044.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • B4976

    BMS-794833

    MET, VEGFR2, Ron, Axl, FLT3 inhibitor.

    ≥98%
  • L8009

    D-Luciferin 1-(4,5-dimethoxy-2-nitrophenyl) Ethyl Ester

    Cell-membrane permeable heterocyclic light-emit...

    ≥95%
  • U6802

    Urapidil Hydrochloride

    5-HT1A agonist, α1-adrenergic antagonist.

    ≥98%
  • P6002

    PP-121

    p110α PI3K, DNA-PK, mTOR, Abl, Hck, Src, VEGFR...

    ≥98%
  • A7462

    Aspartame

    Dipeptide ester, commercial sweetener.

    ≥98%
  • L0350

    Lamivudine

    Nucleoside (thymidine) analog; RT inhibitor.

    ≥99%
  • C0250

    Calcitonin Gene Related Peptide II, human

    Calcitonin-family peptide, involved in vasodila...

    ≥95%
  • F4532

    Flibanserin

    5-HT1A agonist, 5-HT2A antagonist.

    ≥97%
  • N3496

    Nizatidine

    Histamine H2 inverse agonist.

    ≥98%
  • T0253

    Tangeretin

    Polymethoxy flavonoid found in citrus fruits.

    ≥98%
  • R1627

    Regorafenib Anhydrous

    Multikinase inhibitor.

    ≥99%
  • C1844

    Celastrol

    Triterpene isolated Trypterigium wilfordii; HSP...

    ≥98%
  • B0025

    Bafilomycin A1

    Macrolide antibiotic; vacuolar H+ ATPase inhibi...

    ≥90%
  • N0160

    NAP Peptide

    Octapeptide derived from activity-dependent neu...

    ≥95%
  • T0298

    Tazobactam

    β-lactamase inhibitor.

    ≥98%
  • S1968

    Seratrodast

    TxA2 antagonist.

    ≥99%
  • P6800

    Pravastatin Lactone

    Statin; HMG-CoA reductase inhibitor.

    ≥98%
  • C1878

    Cetrimide

    Mixture of quaternary ammonium salts, cationic ...

    ≥98%
  • I7074

    Irsogladine Maleate

    NSAID; COX-1/2 and PDE inhibitor.

    ≥98%
  • W7200

    WS3

    Islet β cell proliferation stimulator.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only