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Ansamitocin P3

Product ID A5472
Cas No. 66547-09-9
Purity ≥70%
Product Unit SizeCostQuantityStock
1 mg $56.70 In stock
5 mg $164.50 In stock
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  • Product Info
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  • Description
  • Product Info
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  • Downloads
  • References
  • Custom Order

Description

Ansamitocin P3 induces microtubule depolymerization by binding tubulin; it exhibits immunomodulatory and anticancer activities. Ansamitocin P3 increases T cell signaling and antigen uptake and decreases regulatory T cell levels in vivo.

Product Info

Cas No.

66547-09-9

Purity

≥70%

Formula

C32H43CIN2O9

Formula Wt.

635.14

Solubility

10mM DMSO

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

A5472 MSDS PDF

Info Sheet

A5472 Info Sheet PDF

References

Martin K, Müller P, Schreiner J, et al. The microtubule-depolymerizing agent ansamitocin P3 programs dendritic cells toward enhanced anti-tumor immunity. Cancer Immunol Immunother. 2014 Sep;63(9):925-38. PMID: 24906866.

Venghateri JB, Gupta TK, Verma PJ, et al. Ansamitocin P3 depolymerizes microtubules and induces apoptosis by binding to tubulin at the vinblastine site. PLoS One. 2013 Oct 4;8(10):e75182. PMID: 24124473.

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