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XL-228

XL-228

Product ID X4400
Cas No. 898280-07-4
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $127.70 In stock
5 mg $269.70 In stock
10 mg $433.90 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

XL-228 is a third generation inhibitor of Abl that shows efficacy in a variety of cell lines, including those exhibiting T315I mutations. XL-228 displays anticancer chemotherapeutic activity and is currently in clinical trials as a potential treatment for chronic myelogenous leukemia (CML).

Product Info

Cas No.

898280-07-4

Purity

≥98%

Formula

C22H31N9O

Formula Wt.

437.54

IUPAC Name

4-N-(5-cyclopropyl-1H-pyrazol-3-yl)-6-(4-methylpiperazin-1-yl)-2-N-[(3-propan-2-yl-1,2-oxazol-5-yl)methyl]pyrimidine-2,4-diamine

Solubility

Soluble in DMSO

Appearance

White Powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

X4400 MSDS PDF

Info Sheet

X4400 Info Sheet PDF

References

Noronha G, Cao J, Chow CP, et al. Inhibitors of ABL and the ABL-T315I mutation. Curr Top Med Chem. 2008;8(10):905-21. PMID: 18673174.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

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