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Abiraterone

Abiraterone

Product ID A0534
Cas No. 154229-19-3
Purity ≥99%
Product Unit SizeCostQuantityStock
1 mg $90.30 In stock
5 mg $149.00 In stock
25 mg $462.00 In stock
100 mg $1,312.50 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Abiraterone is an anticancer chemotherapeutic compound that is used to treat castration-resistant prostate cancer. Abiratone inhibits the enzyme Cytochrome p450 17α-hydroxylase (Cyp17), reducing androgen production. This compound may also directly decrease levels of androgen receptor protein expression and inhibit eIF4F signaling.

Product Info

Cas No.

154229-19-3

Purity

≥99%

Formula

C24H31NO

Formula Wt.

349.51

Chemical Name

(3beta)-17-(3-pyridinyl)-androsta-5,16-dien-3-ol

IUPAC Name

(3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-pyridin-3-yl-2,3,4,7,8,9,11,12, 14,15-decahydro-1H-cyclopenta[a]phenanthren-3-ol

Solubility

MeOH

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

A0534 MSDS PDF

Info Sheet

A0534 Info Sheet PDF

References

Ryan CJ, Cheng ML. Abiraterone acetate for the treatment of prostate cancer. Expert Opin Pharmacother. 2013 Jan;14(1):91-6. PMID: 23199349.

Rehman Y, Rosenberg JE. Abiraterone acetate: oral androgen biosynthesis inhibitor for treatment of castration-resistant prostate cancer. Drug Des Devel Ther. 2012;6:13-8. PMID: 22291466.

Soifer HS, Souleimanian N, Wu S, et al. Direct regulation of androgen receptor activity by potent CYP17 inhibitors in prostate cancer cells. J Biol Chem. 2012 Feb 3;287(6):3777-87. PMID: 22174412.

Custom Order

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