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Acetyl-α-Endorphin

Product ID E5215
Cas No.
Purity ≥95%
Product Unit SizeCostQuantityStock
1 mg $126.00 Please Inquire
2 mg $214.30 Please Inquire
5 mg $377.90 Please Inquire
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  • Description
  • Product Info
  • Shipping and Storage
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  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
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Description

α-Endorphin exhibits much of the same properties as β-endorphin, being an endogenous opioid peptide that acts as an agonist at μ-opioid receptors (μORs) and exhibits immunomodulatory, neuromodulatory, antidepressant, and antinociceptive/analgesic activities. This peptide, like other endogenous opioids, plays a significant role in reward and reinforcement signaling, especially in brain regions such as the ventral tegmental area (VTA) and nucleus accumbens (NAcc). α-Endorphin release is induced during exercise and shows antidepressant activity in clinical studies.

Product Info

Purity

≥95%

Formula

C79H122N18O27S

Formula Wt.

1788.02

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

Info Sheet

E5215 Info Sheet PDF

References

Charbogne P, Kieffer BL, Befort K. 15 years of genetic approaches in vivo for addiction research: Opioid receptor and peptide gene knockout in mouse models of drug abuse. Neuropharmacology. 2014 Jan;76 Pt B:204-17. PMID: 24035914.

Dinas PC, Koutedakis Y, Flouris AD. Effects of exercise and physical activity on depression. Ir J Med Sci. 2011 Jun;180(2):319-25. PMID: 21076975.

Horváth G, Mécs L. Antinociception by endogenous ligands at peripheral level. Ideggyogy Sz. 2011 Mar 30;64(5-6):193-207. PMID: 21688721.

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