• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
all-trans-Retinol

all-trans-Retinol

Product ID R1876
Cas No. 68-26-8
Purity ≥95%
Product Unit SizeCostQuantityStock
25 mg $65.40 In stock
100 mg $92.00 In stock
250 mg $204.30 In stock
500 mg $289.70 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

All-trans retinol is a diterpenoid component of vitamin A. This compound is an essential vitamin and is necessary for effective vision, skin health, and bone growth. Retinol and its metabolites activate retinoic acid receptors (RARs) and retinoid X receptors (RXRs), both of which have multiple isotypes and isoforms. During fetal development, retinol influences cellular differentiation in a variety of ways. Retinol also plays a role in cancer stem cell differentiation, mediated through ERK1/2 signaling. In the immune system, retinol appears to play a protective role in autoimmune diseases such as multiple sclerosis and encephalopathy, downregulating pro-inflammatory responses stimulated by Th1 and Th17 cells.

 

Product Info

Cas No.

68-26-8

Purity

≥95%

Formula

C20H30O

Formula Wt.

286.45

Chemical Name

3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclchexen-1-yl)-2,- 4,6,8-nonatetraen-1-ol

IUPAC Name

(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6, 8-tetraen-1-ol

Synonym

Alphasterol, Retinol, Avitol, Vitamin A

Melting Point

63-64°C

Solubility

Soluble in alcohol, methanol, chloroform, ether, fats or oils.

Appearance

Yellow to red Sticky Solid

Shipping and Storage

Store Temp

-20°C

Ship Temp

Blue Ice

Downloads

MSDS

R1876 MSDS PDF

Info Sheet

R1876 Info Sheet PDF

References

Friedman MD, Jeevan DS, Tobias M, et al. Targeting cancer stem cells in glioblastoma multiforme using mTOR inhibitors and the differentiating agent all-trans retinoic acid. Oncol Rep. 2013 Oct;30(4):1645-50. PMID: 23877261.

Farhangi MA, Keshavarz SA, Eshraghian M, et al. Vitamin a supplementation and serum Th1- and th2-associated cytokine response in women. J Am Coll Nutr. 2013 Aug;32(4):280-5. PMID: 24024773.

Sharma RB, Wang Q, Khillan JS. Amplification of tumor inducing putative cancer stem cells (CSCs) by vitamin A/retinol from mammary tumors. Biochem Biophys Res Commun. 2013 Jul 12;436(4):625-31. PMID: 23764401.

Zhan XX, Liu Y, Yang JF, et al. All-trans-retinoic acid ameliorates experimental allergic encephalomyelitis by affecting dendritic cell and monocyte development. Immunology. 2013 Apr;138(4):333-45. PMID: 23181351.

Duester G. Retinoic acid synthesis and signaling during early organogenesis. Cell. 2008 Sep 19;134(6):921-31. PMID: 18805086.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • F334451

    Filipin Complex

    A probe for cholesterol in biological membranes...

    ≥97%
  • J0378

    Jatrorrhizine

    Alkaloid compound originally found in Corydalis...

    ≥98%
  • A4445

    Allopurinol

    Purine (hypoxanthine) analog; xanthine oxidase ...

    ≥98%
  • B5728

    Bohemine

    Purine derivative; CDK inhibitor.

    ≥98%
  • T9945

    Tylosin Tartrate

    Macrolide; peptidyl transferase inhibitor, prot...

    ≥90%
  • J889290

    JWH 133

    Cannabinoid receptor 2 selective agonist.

    ≥95%
  • P0244

    Palbociclib Hydrochloride

    CDK4/6 inhibitor.

    ≥99%
  • A0818

    15-Acetoxyscirpenol

    Trichothecene mycotoxin produced by Fusarium.

    ≥97%
  • C2802

    CH5132799

    p110α PI3K inhibitor.

    ≥98%
  • T4400

    TL-32711

    Smac mimetic; IAP inhibitor.

    ≥98%
  • E6880

    Erucin

    Isothiocyanate found in cruciferous vegetables,...

    ≥98%
  • E7228

    Ethacridine Lactate Monohydrate

    Aromatic acridine derivative, DNA intercalator....

    ≥98%
  • G3461

    Ginsenoside F2

    Triterpene saponin found in species of Panax.

    ≥98%
  • A4534

    Aliskiren Hemifumarate

    Renin inhibitor.

    ≥98%
  • D3201

    Diallyl Sulfide

    Organosulfur found in garlic.

    ≥98%
  • M3321

    Mifepristone

    Synthetic steroid, contraceptive; PR and glucoc...

    ≥98%
  • D1644

    Deltorphin I

    Opioid peptide; δOR agonist.

    ≥98%
  • D1695

    Dexamethasone Phosphate Sodium

    Steroid; glucocorticoid agonist.

    ≥98%
  • K3352

    Kinetensin

    Peptide, neurotensin analog.

    ≥95%
  • M568262

    Mogrol

    Triterpenoid

    ≥99%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only